Stochastic segmentation models for array-based comparative genomic hybridization data analysis
Array-based comparative genomic hybridization (array-CGH) is a high throughput, high
resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically …
resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically …
Bayesian random segmentation models to identify shared copy number aberrations for array CGH data
Array-based comparative genomic hybridization (aCGH) is a high-resolution, high-
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
Computational methods for the analysis of array comparative genomic hybridization
Array comparative genomic hybridization (array CGH) is a technique for assaying the copy
number status of cancer genomes. The widespread use of this technology has lead to a …
number status of cancer genomes. The widespread use of this technology has lead to a …
Bayesian hidden Markov modeling of array CGH data
Genomic alterations have been linked to the development and progression of cancer. The
technique of comparative genomic hybridization (CGH) yields data consisting of …
technique of comparative genomic hybridization (CGH) yields data consisting of …
BioHMM: a heterogeneous hidden Markov model for segmenting array CGH data
We have developed a new method (BioHMM) for segmenting array comparative genomic
hybridization data into states with the same underlying copy number. By utilizing a …
hybridization data into states with the same underlying copy number. By utilizing a …
A pseudolikelihood approach for simultaneous analysis of array comparative genomic hybridizations
DA Engler, G Mohapatra, DN Louis, RA Betensky - Biostatistics, 2006 - academic.oup.com
DNA sequence copy number has been shown to be associated with cancer development
and progression. Array-based comparative genomic hybridization (aCGH) is a recent …
and progression. Array-based comparative genomic hybridization (aCGH) is a recent …
A segmentation/clustering model for the analysis of array CGH data
Microarray-CGH (comparative genomic hybridization) experiments are used to detect and
map chromosomal imbalances. A CGH profile can be viewed as a succession of segments …
map chromosomal imbalances. A CGH profile can be viewed as a succession of segments …
Continuous-index hidden Markov modelling of array CGH copy number data
Motivation: In recent years, a range of techniques for analysis and segmentation of array
comparative genomic hybridization (aCGH) data have been proposed. For array designs in …
comparative genomic hybridization (aCGH) data have been proposed. For array designs in …
Analysis of array CGH data for cancer studies using fused quantile regression
Y Li, J Zhu - Bioinformatics, 2007 - academic.oup.com
Motivation: The identification of DNA copy number changes provides insights that may
advance our understanding of initiation and progression of cancer. Array-based comparative …
advance our understanding of initiation and progression of cancer. Array-based comparative …
A comparison study: applying segmentation to array CGH data for downstream analyses
H Willenbrock, J Fridlyand - Bioinformatics, 2005 - academic.oup.com
Motivation: Array comparative genomic hybridization (CGH) allows detection and mapping
of copy number of DNA segments. A challenge is to make inferences about the copy number …
of copy number of DNA segments. A challenge is to make inferences about the copy number …