P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

EB Zhang, DD Yin, M Sun, R Kong, XH Liu… - Cell death & …, 2014 - nature.com
Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified
at a rapid pace. These RNAs have critical roles in diverse biological processes, including …

Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2

MD Huang, WM Chen, FZ Qi, M Sun, TP Xu, P Ma… - Molecular cancer, 2015 - Springer
Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death worldwide, and the biology of this cancer remains poorly understood. Recent …

Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2

PC Lin, HD Huang, CC Chang, YS Chang, JC Yen… - BMC cancer, 2016 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis,
and lncRNA taurine-upregulated gene 1 (TUG1) has been proven to be associated with …

Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57

E Zhang, X He, D Yin, L Han, M Qiu, T Xu, R Xia… - Cell death & …, 2016 - nature.com
Recent evidence highlights long noncoding RNAs (lncRNAs) as crucial regulators of cancer
biology that contribute to tumorigenesis. LncRNA TUG1 was initially detected in a genomic …

TUG 1: a pivotal oncogenic long non‐coding RNA of human cancers

Z Li, J Shen, MTV Chan, WKK Wu - Cell proliferation, 2016 - Wiley Online Library
Long non‐coding RNA s (lnc RNA s) are a group greater than 200 nucleotides in length. An
increasing number of studies has shown that lnc RNA s play important roles in diverse …

Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma

Y Xu, J Wang, M Qiu, L Xu, M Li, F Jiang, R Yin, L Xu - Tumor Biology, 2015 - Springer
Esophageal squamous cell carcinoma (ESCC) is one of the prevalent and deadly cancers
worldwide, especially in Eastern Asia. The prognosis of ESCC remains poor; thus, it is still …

Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

Y Niu, F Ma, W Huang, S Fang, M Li, T Wei, L Guo - Molecular cancer, 2017 - Springer
Background Taurine upregulated gene1 (TUG1) as a 7.1-kb lncRNA, has been shown to
play an oncogenic role in various cancers. However, the biological functions of lncRNA …

The long non-coding RNA TUG1 indicates a poor prognosis for colorectal cancer and promotes metastasis by affecting epithelial-mesenchymal transition

J Sun, C Ding, Z Yang, T Liu, X Zhang, C Zhao… - Journal of translational …, 2016 - Springer
Background Long intergenic non-coding RNAs (lncRNAs) are a class of non-coding RNAs
that are involved in gene expression regulation. Taurine up-regulated gene 1 (TUG1) is a …

[HTML][HTML] Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in …

J Tan, K Qiu, M Li, Y Liang - FEBS letters, 2015 - Elsevier
LncRNAs have a critical role in the regulation of cellular processes such as cancer
progression and metastasis. In the present study, we confirmed that TUG1 was …

[HTML][HTML] Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition

S Guo, L Zhang, Y Zhang, Z Wu, D He, X Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Long non-coding RNA taurine up-regulated gene 1 (TUG1) emerges as new players in gene
regulation in several cancers; however, its mechanism of action in non-small cell lung …