Modulation of B-cell exosome proteins by gamma herpesvirus infection

DG Meckes Jr, HP Gunawardena… - Proceedings of the …, 2013 - National Acad Sciences
The human gamma herpesviruses, Kaposi sarcoma-associated virus (KSHV) and EBV, are
associated with multiple cancers. Recent evidence suggests that EBV and possibly other …

Herpesviruses hijack host exosomes for viral pathogenesis

S Sadeghipour, RA Mathias - Seminars in cell & developmental biology, 2017 - Elsevier
Herpesviruses are remarkable pathogens possessing elaborate mechanisms to seize
various host cellular components for immune evasion, replication, and virion egress. As …

Exosomal communication goes viral

DG Meckes Jr - Journal of virology, 2015 - Am Soc Microbiol
Exosomes are small vesicles secreted from cells that participate in intercellular
communication events. Accumulating evidence demonstrates that host exosome pathways …

[HTML][HTML] Pathogenic role of exosomes in Epstein-Barr virus (EBV)-associated cancers

SY Teow, K Liew, ASB Khoo, SC Peh - International journal of …, 2017 - ncbi.nlm.nih.gov
Abstract Exosomes are 40-to 100-nm membrane-bound small vesicles that carry a great
variety of cellular cargoes including proteins, DNA, messenger RNAs (mRNAs), and …

Microvesicles and viral infection

DG Meckes Jr, N Raab-Traub - Journal of virology, 2011 - Am Soc Microbiol
Cells secrete various membrane-enclosed microvesicles from their cell surface (shedding
microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly …

Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells

A Nanbo, E Kawanishi, R Yoshida… - Journal of virology, 2013 - Am Soc Microbiol
ABSTRACT Epstein-Barr virus (EBV), a human gammaherpesvirus, establishes a lifelong
latent infection in B lymphocytes and epithelial cells following primary infection. Several …

Exosomes released in vitro from Epstein–Barr virus (EBV)-infected cells contain EBV-encoded latent phase mRNAs

A Canitano, G Venturi, M Borghi, MG Ammendolia… - Cancer letters, 2013 - Elsevier
EBV is a human herpesvirus associated with a number of malignancies. Both
lymphoblastoid cell lines (LCLs), and EBV-infected nasopharyngeal carcinoma (NPC) cells …

Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma

H Higuchi, N Yamakawa, KI Imadome… - Blood, The Journal …, 2018 - ashpublications.org
Epstein-Barr virus (EBV) causes various diseases in the elderly, including B-cell lymphoma
such as Hodgkin's lymphoma and diffuse large B-cell lymphoma. Here, we show that EBV …

[HTML][HTML] Profile of exosomal and intracellular microRNA in gamma-herpesvirus-infected lymphoma cell lines

S Hoshina, T Sekizuka, M Kataoka, H Hasegawa… - PloS one, 2016 - journals.plos.org
Exosomes are small vesicles released from cells, into which microRNAs (miRNA) are
specifically sorted and accumulated. Two gamma-herpesviruses, Kaposi sarcoma …

[HTML][HTML] Epstein-Barr virus-encoded small RNAs (EBERs) are present in fractions related to exosomes released by EBV-transformed cells

W Ahmed, PS Philip, S Tariq, G Khan - PloS one, 2014 - journals.plos.org
Epstein-Barr virus (EBV) is an oncogenic herpesvirus associated with a number of human
malignancies of epithelial and lymphoid origin. However, the mechanism of oncogenesis is …