In animal models of Alzheimer's disease (AD), amyloid-β fragments interfere with
mechanisms of cortical plasticity such as long-term potentiation (LTP) and long-term …

OBJECTIVE: Mechanisms of synaptic plasticity like long term depression (LTD) are altered
in experimental models of Alzheimer's disease (AD). LTD-like plasticity mechanisms has not …

Objective Alzheimer's disease (AD) is considered an age‐related disorder. However, it is
unclear whether AD induces the same pathological and neurophysiological modifications in …

Background: Mechanisms of cortical plasticity have been recently investigated in
Alzheimer's disease (AD) patients with transcranial magnetic stimulation protocols showing …

Alzheimer's disease (AD) is a neurodegenerative process characterized by progressive
neuronal degeneration, reduced levels of neurotransmitters, and altered forms of synaptic …

Background Alzheimer's disease (AD) is characterized by a primary impairment of long-term
declarative memory caused by deposition of misfolded protein aggregates. Experimental …

BACKGROUND: The aim of this study was to determine whether neocortical long-term
potentiation (LTP) is deficient in patients with Alzheimer's disease (AD) and in amyloid …

Cerebrospinal fluid (CSF) concentrations of amyloid-ß (Aß), total tau (t-tau), and
phosphorylated tau proteins are associated with different clinical progression in Alzheimer's …

We investigated the neuroprotective effect of regular treadmill exercise training on long-term
memory and its correlate: the late-phase long-term potentiation (L-LTP) and plasticity-and …

Deterioration of motor and cognitive performance with advancing age is well documented,
but its cause remains unknown. Animal studies dating back to the late 1970s reveal that age …