Drug delivery systems

K NIKANDER - Journal of Aerosol Medicine, 1994 - liebertpub.com
Nebulizers, both jet and ultrasonic, were originally designed to convert a liquid solution into
an aerosol. During recent years suspensions for nebulization have been developed and …

Formulations and nebulizer performance.

TG O'Riordan - Respiratory care, 2002 - europepmc.org
To deliver a drug by nebulization, the drug must first be dispersed in a liquid (usually
aqueous) medium. After application of a dispersing force (either a jet of gas or ultrasonic …

In vitro determination of inhaled mass and particle distribution for budesonide nebulizing suspension

GC Smaldone, M Cruz-Rivera… - Journal of aerosol …, 1998 - liebertpub.com
Nebulized delivery of aerosols to the lung is a complex process dependent on the device,
the drug preparation, the patient's breathing pattern and other factors. It is difficult to predict …

The conventional ultrasonic nebulizer proved inefficient in nebulizing a suspension

K Nikander, M Turpeinen, P Wollmer - Journal of aerosol medicine, 1999 - liebertpub.com
ABSTRACT A study was undertaken to compare the amount of nebulized budesonide
suspension and nebulized terbutaline sulphate solution inhaled by healthy adult subjects …

Ultrasonic nebulisers for pulmonary drug delivery

KMG Taylor, ONM McCallion - International journal of pharmaceutics, 1997 - Elsevier
Nebulisers are widely used to generate therapeutic aerosols for inhalation therapy. In this
paper the factors determining aerosol size and drug output from ultrasonic nebulisers are …

Ultrasonic nebulization system for respiratory drug delivery

TS Wiedmann, A Ravichandran - Pharmaceutical development and …, 2001 - Taylor & Francis
An ultrasonic spray system was tested for the production of aerosols for ultimate use in the
respiratory delivery of drug to animals. A Sono-Tek ultrasonic spray system was mounted on …

Design principles of liquid nebulization devices currently in use.

JL Rau - Respiratory Care, 2002 - europepmc.org
Liquid nebulization is a common method of medical aerosol generation. Nebulizers are of 2
types: jet (or pneumatic) small-volume nebulizer, and ultrasonic nebulizer. Jet nebulizers are …

Drug delivery from the Turbuhaler and Nebuhaler pressurized metered dose inhaler to various age groups of children with asthma

L AGERTOFT, S PEDERSEN… - Journal of aerosol …, 1999 - liebertpub.com
ABSTRACT A total of 198 children aged 3 to 15 years inhaled a single dose of 200 μg
budesonide from a Nebuhaler pressurized metered dose inhaler (pMDI) and a Turbuhaler …

Behavior of nebulizing solutions and suspensions

M DAHLBÄCK - Journal of Aerosol Medicine, 1994 - liebertpub.com
ABSTRACT A compressed air source is needed to run a jet nebulizer; its operating pressure
affects the aerosol flow through the nebulizer, the quantity of drug and/or solution leaving the …

Drug nebuliser design and performance: breath enhanced jet vs. constant output jet vs. ultrasonic

JH Dennis - Journal of Aerosol Medicine, 1995 - liebertpub.com
Output Jet Vs. Ultrasonic Page 1 JOURNAL OF AEROSOL MEDICINE Volume 8, Number 3,
1995 Mary Ann Liebert, Inc. Drug Nebuliser Design and Performance: Breath Enhanced Jet …