The molecular mechanisms that determine the interactions between cells and their
microenvironment are of central importance to the normal development and function of …

Publisher Summary Heparan sulfate (HS) proteoglycans represent a large family of both cell
surface and pericellular macromolecules. Proteoglycans are proteins that contain …

Some of the proteins that are expressed at the cell surface carry one or more
glycosaminoglycan chains. A growing body of evidence suggests that these molecules are …

A. Introduction Heparan sulfate proteoglycans(HSPGs) are widely distributed among animal
cells, as a basic component of cell surface molecules and as a major constituent of …

Heparan sulphate (HS)‐containing proteoglycans (HS‐PGs) are present at the surface of
nearly all adherent mammalian cells. The principal mode of attachment is by way of the …

Heparan sulfate proteoglycans are complex molecules composed of a core protein with
covalently attached glycosaminoglycan chains. While the protein part determines …

Proteoglycans (primarily heparan sulphate proteoglycans) are found at the surface of most
adherent eukaryotic cells. Earlier studies suggest that these molecules can be associated …

Heparan sulphate proteoglycans (HSPGs) are normally the most abundant PG components
of cell surfaces and basement membranes (1, 2). At the molecular level five core proteins …

Proteoglycans-protein molecules that are covalently modified with sulphated
glycosaminoglycans-are widespread throughout mammalian tissues both as extracellular …

Hcparan sulphate proteoglycans occur in close association with cells. They accumulate at
cell-cell and cell-matrix interfaces, both as plasma-membrane-associated molecules and as …