Background Red blood cell (RBC) alloimmunization is a major challenge to repeated
transfusions in β-thalassemia-major patients. The aim of this study was to evaluate the …

Abstract Background and Objective: The mainstay of management of severe β-thalassemia
remains lifelong blood transfusion. The development of one or more alloantibody against …

Background Thalassemia major is a common health problem in Egypt. However, limited
data are available on the frequency of red blood cell (RBC) alloimmunization and …

Objective We aimed to find out the frequency of alloimmunization in multitransfused β-
thalassemic patients, the most common alloantibodies involved, factors contributing to their …

The development of hemolytic erythrocyte alloantibodies and autoantibodies complicates
transfusion therapy in thalassemia patients. These antibodies ultimately increase the need …

The development of erythrocyte alloantibodies complicates transfusion therapy in β
thalassemia major patients. These antibodies increase the need for blood and intensify …

Materials and Methods: This prospective, cross-sectional study was conducted at the
Department of Blood Transfusion Services and Thalassemia Centre of Pakistan Institute of …

Background Beta thalassemia is considered a severe, progressive anemia, which needs
regular transfusions for life expectancy. One of the most important complications of regular …

BACKGROUND β‐Thalassemia is considered the most common chronic hemolytic anemia
in Egypt. Alloimmunization can lead to serious clinical complications in transfusion …

Background: Thalassemia is one of the most common monogenic disorders characterized
by reduced production of globin chains. Although regular red blood cell (RBC) transfusion …