Early improvement as a predictor of eventual antidepressant treatment response in severely depressed inpatients

M Vermeiden, AM Kamperman, ME Vulink… - …, 2015 - Springer
Rationale Traditionally, the therapeutic effect of antidepressants is thought to take several
weeks. However, several studies found evidence of early drug response occurring within the …

Does early improvement triggered by antidepressants predict response/remission?—Analysis of data from a naturalistic study on a large sample of inpatients with …

V Henkel, F Seemüller, M Obermeier, M Adli… - Journal of affective …, 2009 - Elsevier
BACKGROUND: Delayed onset of efficacy of antidepressants and a high proportion of
depressed patients being poor or non-responders to antidepressants are well known clinical …

[HTML][HTML] Early response to antidepressant medications in adults with major depressive disorder: a naturalistic study and odds of remission at 14 weeks

HG Belanger, C Lee, Z Poliacoff, CT Gupta… - Journal of Clinical …, 2023 - journals.lww.com
Early Response to Antidepressant Medications in Adults With... : Journal of Clinical
Psychopharmacology Early Response to Antidepressant Medications in Adults With Major …

Early improvement under mirtazapine and paroxetine predicts later stable response and remission with high sensitivity in patients with major depression

A Szegedi, MJ Muller, I Anghelescu… - Journal of Clinical …, 2003 - psychiatrist.com
Objective: Current clinical knowledge holds that antidepressants have a delayed onset of
efficacy. However, the delayed onset hypothesis has been questioned recently by survival …

Early improvement in the first 2 weeks as a predictor of treatment outcome in patients with major depressive disorder: a meta-analysis including 6562 patients.

A Szegedi, WT Jansen… - Journal of Clinical …, 2009 - psychiatrist.com
Objective: New evidence indicates that treatment response can be predicted with high
sensitivity after 2 weeks of treatment. Here, we assess whether early improvement with …

Time course of response to antidepressants: predictive value of early improvement and effect of additional psychotherapy

D van Calker, I Zobel, P Dykierek, CM Deimel… - Journal of Affective …, 2009 - Elsevier
BACKGROUND: The full response to antidepressant pharmacotherapy is evident only after
several weeks, but considerable improvements may already be visible within the first two …

Onset, time course and trajectories of improvement with antidepressants

RW Lam - European Neuropsychopharmacology, 2012 - Elsevier
There is still considerable controversy about the onset and time course of improvement with
antidepressants in the treatment of major depressive disorder. Previous studies suggested a …

Accelerating response to antidepressant treatment in depression: a review and clinical suggestions

S Nakajima, T Suzuki, K Watanabe, H Kashima… - Progress in Neuro …, 2010 - Elsevier
OBJECTIVE: The primary objective of this article is to review the literature regarding the
speed of response to antidepressant drugs and potential strategies to accelerate the …

Initial response to active drug and placebo predicts outcome of antidepressant treatment

S Priebe, M Bröker - European psychiatry, 1997 - cambridge.org
In this study we tested whether initial clinical change (ICC) and initial subjective response
(ISR) predict the outcome of antidepressant pharmacotherapy and whether ICC and ISR as …

The early improvement of depressive symptoms as a potential predictor of response to antidepressants in depressive patients who failed to respond to previous …

M Bares, T Novak, M Kopecek, P Stopkova, J Kozeny… - European …, 2012 - Elsevier
INTRODUCTION: Current studies suggest that improvement of depressive symptoms after 2
weeks of treatment could predict the subsequent response. The aim of our study was to …