Longitudinal characterization of motor and cognitive deficits in a model of penetrating ballistic-like brain injury

DA Shear, XCM Lu, MC Bombard… - Journal of …, 2010 - liebertpub.com
Traumatic brain injury (TBI) produces a wide range of motor and cognitive changes. While
some neurological symptoms may respond to therapeutic intervention during the initial …

Motor and cognitive function evaluation following experimental traumatic brain injury

ST Fujimoto, L Longhi, KE Saatman… - … & biobehavioral reviews, 2004 - Elsevier
Traumatic brain injury (TBI) in humans may cause extensive sensorimotor and cognitive
dysfunction. As a result, many TBI researchers are beginning to assess behavioral …

A comparison of two cognitive test paradigms in a penetrating brain injury model

AR Davis, DA Shear, Z Chen, XCM Lu… - Journal of neuroscience …, 2010 - Elsevier
A rat model of penetrating ballistic-like brain injury (PBBI) was recently established to study
military-relevant severe traumatic brain injury (TBI). The purpose of this study was to conduct …

Longitudinal assessment of gait abnormalities following penetrating ballistic-like brain injury in rats

A Mountney, LY Leung, R Pedersen, D Shear… - Journal of neuroscience …, 2013 - Elsevier
Traumatic brain injury (TBI) results in enduring motor and cognitive dysfunction. Although
gait disturbances have been documented among TBI patients, few studies have profiled gait …

Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions

MD Lindner, MA Plone, CK Cain, B Frydel… - Journal of …, 1998 - liebertpub.com
Cognitive deficits are the most enduring and disabling sequelae of human traumatic brain
injury (TBI), but quantifying the magnitude, duration, and pattern of cognitive deficits …

Persistent behavioral deficits in rats after parasagittal fluid percussion injury

SL Sell, K Johnson, DS DeWitt… - Journal of neurotrauma, 2017 - liebertpub.com
Although traumatic brain injury (TBI) is now considered a chronic disease, few studies have
investigated the long-term behavioral deficits elicited by a well-established rodent model of …

Severity profile of penetrating ballistic-like brain injury on neurofunctional outcome, blood–brain barrier permeability, and brain edema formation

DA Shear, XCM Lu, R Pedersen, G Wei… - Journal of …, 2011 - liebertpub.com
This study evaluated the injury severity profile of unilateral, frontal penetrating ballistic-like
brain injury (PBBI) on neurofunctional outcome, blood–brain barrier (BBB) permeability, and …

Severity level and injury track determine outcome following a penetrating ballistic-like brain injury in the rat

AJ Williams, GSF Ling, FC Tortella - Neuroscience letters, 2006 - Elsevier
Penetrating ballistic brain injury (PBBI) is a high-energy transfer wound causing direct
damage to the cerebrum. Outcome is directly related to the ballistic's anatomical path and …

Initial Severity of Injury Has Little Effect on the Temporal Profile of Long-Term Deficits in Locomotion, Anxiety, and Cognitive Function After Diffuse Traumatic Brain …

F Corrigan, A Arulsamy, SR Shultz, DK Wright… - Neurotrauma …, 2023 - liebertpub.com
Traumatic brain injury (TBI) is associated with persistent impairments in multiple domains,
including cognitive and neuropsychiatric function. Previous literature has suggested that the …

Experimental traumatic brain injury results in long-term recovery of functional responsiveness in sensory cortex but persisting structural changes and sensorimotor …

VPA Johnstone, DK Wright, K Wong… - Journal of …, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of death worldwide. In recent studies, we
have shown that experimental TBI caused an immediate (24-h post) suppression of …