Since atherosclerosis has been proven to be an inflammatory disease, it is obvious that the
proper treatment for dyslipidemia should not only correct lipid parameters but also inhibit …

Methods Ten patients with HLPIIb were treated with micronized fenofibrate for 1 month.
Before and after treatment, the cytokine levels were measured by the ELISA method. To …

This study was designed to investigate whether fibrates produce lymphocyte‐suppressing
and systemic anti‐inflammatory effects in statin‐treated pre‐diabetic patients. The study …

More and more recent studies demonstrate the pleiotropic effects of fibrates. Except lowering
plasma lipid levels they can influence blood coagulation abnormalities and stabilise …

Fibrates and omega‐3 fatty acids have been used for many years in the treatment of
increased triglyceride levels. Unfortunately, pleiotropic effects of these agents in patients …

Abstract Both 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors
(statins) as well as peroxisome proliferator-activated receptor (PPAR) α activators (fibrates) …

In order to investigate the effect of fenofibrate on microcirculation, 16 patients (5 female, 11
male, age 58+/-8 years) were studied with the aid of nailfold capillaroscopy before and after …

Purpose The PPAR-alpha agonists (fibrates) are commonly used in the treatment of
dyslipidemia. It has been hypothesized that the cardio-protective effects of fibrates are …

Background: Atherosclerosis is the leading cause of death in developed countries. Although
the mechanisms that underlie this process are not well defined, it has been proposed that …

The aim of our study was to compare the effect of simvastatin and fenofibrate treatment on
the secretory function of human monocytes and lymphocytes and on systemic inflammation …