Secukinumab demonstrates sustained efficacy in clearing skin and improving patient-reported outcomes in patients with moderate-to-severe psoriasis through 2 years …

D Thaçi, L Puig, K Reich, TF Tsai, S Tyring… - Journal of the American …, 2019 - jaad.org
2. Dodiuk-Gad RP, Olteanu C, Feinstein A, et al. Major psychological complications and
decreased health-related quality of life among survivors of Stevens-Johnson syndrome and …

Off-label high-dose secukinumab for the treatment of moderate-to-severe psoriasis

M Phung, A Ighani… - Journal of …, 2019 - journals.sagepub.com
Background: Secukinumab is an anti-IL-17A monoclonal antibody approved for the
treatment of moderate-to-severe psoriasis in adult patients. Despite its favourable safety and …

Efficacy of secukinumab without the initial weekly loading dose in patients with chronic plaque psoriasis

P Gisondi, M Rovaris, S Piaserico… - British Journal of …, 2020 - academic.oup.com
Background Secukinumab is administered at the labelled dose of 300 mg at weeks 0, 1, 2, 3,
4 (loading dose) and every 4 weeks thereafter. Objectives To investigate the efficacy of …

[PDF][PDF] Secukinumab retreatment shows rapid recapture of treatment response: an analysis of a phase 3 extension trial in psoriasis

A Blauvelt, K Reich, RB Warren, B Sigurgeirsson… - J Am Acad …, 2017 - annenberg.net
Secukinumab Retreatment Shows Rapid Recapture of Treatment Response: an Analysis of a
Phase 3 Extension Trial in Psoriasis 4879 Page 1 Secukinumab Retreatment Shows Rapid …

Effectiveness and safety of secukinumab in patients with moderate‐severe psoriasis: a multicenter real‐life study

A Carpentieri, P Mascia, M Fornaro… - Dermatologic …, 2020 - Wiley Online Library
This study assessed the effectiveness and safety of secukinumab in patients with moderate‐
severe psoriasis vulgaris in a real‐world setting. A total of 120 patients (35.8% women; …

Real‐world data from a single Greek centre on the use of secukinumab in plaque psoriasis: effectiveness, safety, drug survival, and identification of patients that …

N Rompoti, P Sidiropoulou, P Panagakis… - Journal of the …, 2020 - Wiley Online Library
Background Few studies have investigated the long‐term outcomes of secukinumab in real‐
life psoriasis treatment where diverse patient profiles require a personalized approach …

Profile of secukinumab in the treatment of psoriasis: current perspectives

M Roman, VK Madkan, MW Chiu - Therapeutics and clinical risk …, 2015 - Taylor & Francis
Secukinumab (Cosentyx™) is a human monoclonal IgG1k antibody that has been
developed to target and block the actions of IL-17A. It is known that this cytokine is elevated …

Effectiveness and safety of secukinumab in 69 patients with moderate to severe plaque psoriasis: a retrospective multicenter study

JF Schwensen, A Clemmensen, C Sand… - Dermatologic …, 2017 - Wiley Online Library
Abstract Secukinumab (anti‐IL17A) is effective as treatment for moderate to severe plaque
psoriasis, but real‐life data on effectiveness and safety lack. We aimed to present real‐life …

Impact of secukinumab on patient-reported outcomes in biologic-naive patients with psoriasis in a US real-world setting

B Strober, D Patil, RR McLean… - Journal of …, 2022 - Taylor & Francis
Objective To describe real-world baseline characteristics and patient-reported outcomes
(PROs) at 6-month and 12-month follow-up visits among patients with psoriasis who initiated …

Effects of secukinumab on metabolic and liver parameters in plaque psoriasis patients

S Gerdes, A Pinter, C Papavassilis… - Journal of the …, 2020 - Wiley Online Library
Background Psoriasis is associated with metabolic, liver and cardiovascular comorbidity.
Secukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin …