The number of long noncoding RNAs (lncRNAs) with characterized developmental and
cellular functions continues to increase, but our understanding of the molecular mechanisms …

Beyond the handful of classic and well-characterized long noncoding RNAs (lncRNAs),
more recently, hundreds of thousands of lncRNAs have been identified in multiple species …

The functionality of long noncoding RNAs (lncRNAs) is disputed. In general, lncRNAs are
under weak selective pressures, suggesting that the majority of lncRNAs may be …

A large proportion of the cellular transcriptome of higher vertebrates consists of non-protein
coding transcripts, among them the long noncoding RNAs (lncRNAs). Although lncRNAs are …

Eukaryotic genomes are pervasively transcribed, with tens of thousands of RNAs emanating
from uni-and bi-directional promoters and from active enhancers. In vertebrates, thousands …

The diversity of lncRNAs has expanded within mammals in tandem with the evolution of
increased brain complexity, suggesting that lncRNAs play an integral role in this process. In …

Over the last decade, the increasing interest in long non-coding RNAs (lncRNAs) has led to
the discovery of these transcripts in multiple organisms. LncRNAs tend to be specifically …

Since decades it has been known that non-protein-coding RNAs have important cellular
functions. Deep sequencing recently facilitated the discovery of thousands of novel …

Long noncoding RNAs (lncRNAs) have emerged as an important class of molecules that
regulate gene expression at epigenetic, transcriptional, and post-transcriptional levels …

The complex universe of RNA transcribed by mammalian cells includes thousands of large
RNA molecules that do not encode for proteins. Despite their lack of coding capacity and …