Highlights•Comparing agents used in ALS animal models by onset, survival and muscle
damage.•Agents are organized by individual mechanisms and effects summarized.•Analysis …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle weakness, paralysis and finally death. The proposed …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by
progressive motor neuron degeneration, muscle weakness, paralysis, and ultimately death …

Amyotrophic lateral sclerosis (ALS) is a clinically severe and fatal neurodegenerative
disease characterized by a loss of both upper and lower motor neurons, resulting in …

Introduction: Amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
disorders, affecting approximately half a million people worldwide. Currently there is no cure …

Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease that rapidly
progresses from mild motor symptoms to severe motor paralysis and premature death. There …

Biomedical researchers interested in amyotrophic lateral sclerosis (ALS) must invoke newly
developing technologies if we are to discover pharmaceutical treatments that will help a …

Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Amyotrophic lateral sclerosis (ALS) is an untreatable and fatal neurodegenerative disease
that is identified by the loss of motor neurons in the spinal cord, brain stem, and motor cortex …

Amyotrophic lateral sclerosis (ALS) is one of the most complex neurodegenerative diseases,
involving both cortical and spinal components of motor neuron circuitry and non-neuronal …