Naringin induces death receptor and mitochondria-mediated apoptosis in human cervical cancer (SiHa) cells

E Ramesh, AA Alshatwi - Food and chemical toxicology, 2013 - Elsevier
Cervical cancer is the second most common female cancer worldwide, and it remains a
challenge to manage preinvasive and invasive lesions. Fruit-based cancer prevention …

Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway

JH Cha, YJ Choi, SH Cha, CH Choi… - Oncology …, 2012 - spandidos-publications.com
Allicin, the main flavor compound in garlic, has anti-carcinogenic activities in a range of
cancer cells, however, the underlying molecular mechanisms are not completely …

The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells

G Ma, C Yang, Y Qu, H Wei, T Zhang… - Chemico-biological …, 2007 - Elsevier
Isorhamnetin is one member of flavonoid components which has been used in the treatment
of heart disease. Recently the in vitro anti-cancer effect of isorhamnetin on human …

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM

JS Woo, GS Choo, ES Yoo… - Molecular …, 2020 - spandidos-publications.com
Apigenin, an aromatic compound, exhibits antioxidant, anti‑inflammatory and anti‑viral
effects. The present study aimed to investigate the effects of apigenin on cell proliferation …

Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-κB mediated activation of bcl-2 in B16F-10 melanoma cells

KA Manu, G Kuttan - International immunopharmacology, 2008 - Elsevier
The objective of this study was to assess the effect of ursolic acid, a triterpene on inducing
apoptosis in B16F-10 melanoma cells. Treatment of B16F-10 cells with nontoxic …

Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA

SY Park, SJ Cho, H Kwon, KR Lee, DK Rhee, S Pyo - Cancer Letters, 2005 - Elsevier
Allicin, the major component of Garlic (Allium sativum) was examined for the ability to induce
apoptosis and the mechanism of the induction of apoptosis in human epithelial carcinoma …

Apigenin-induced apoptosis in A375 and A549 cells through selective action and dysfunction of mitochondria

S Das, J Das, A Samadder… - Experimental …, 2012 - journals.sagepub.com
We isolated apigenin (5, 7, 4'-trihydroxy flavone) from ethanolic extract of Lycopodium
clavatum (LC) used as a homeopathic mother tincture for treatment of various diseases. We …

Study of the cytotoxicity of asiaticoside on rats and tumour cells

FJ Al-Saeedi - BMc cancer, 2014 - Springer
Background Cancer chemoprevention is considered one of the most promising areas in
current cancer research, and asiaticoside, which is derived from the plant Centella asiatica …

Annona muricata leaves induce G1 cell cycle arrest and apoptosis through mitochondria-mediated pathway in human HCT-116 and HT-29 colon cancer cells

SZ Moghadamtousi, H Karimian, E Rouhollahi… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance Annona muricata known as “the cancer killer” has been
widely used in the traditional medicine for the treatment of cancer and tumors. The purpose …

Immune suppressive effect of cinnamaldehyde due to inhibition of proliferation and induction of apoptosis in immune cells: implications in cancer

F Roth-Walter, A Moskovskich, C Gomez-Casado… - PloS one, 2014 - journals.plos.org
Background Besides its anti-inflammatory effects, cinnamaldehyde has been reported to
have anti-carcinogenic activity. Here, we investigated its impact on immune cells. Methods …