Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway

ML Lin, YC Lu, JG Chung, YC Li, SG Wang… - Cancer letters, 2010 - Elsevier
Aloe-emodin (AE), a natural, biologically active compound from the rhizome of Rheum
palmatum, has been shown to induce apoptosis in several cancer cell lines in vitro …

Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95-and mitochondrial-mediated mechanism

C Gajate, F An, F Mollinedo - Clinical cancer research, 2003 - AACR
Aplidine is a promising antitumor agent derived from the Mediterranean tunicate Aplidium
albicans. We have found that Aplidine at nm concentrations (10–100 nm) induced apoptosis …

[HTML][HTML] Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells

HS Lee, HJ Cho, R Yu, KW Lee, HS Chun… - International journal of …, 2014 - mdpi.com
We previously noted that kaempferol, a flavonol present in vegetables and fruits, reduced
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …

[HTML][HTML] Heartwood extract of Acacia catechu induces apoptosis in human breast carcinoma by altering bax/bcl-2 ratio

NB Ghate, B Hazra, R Sarkar… - Pharmacognosy …, 2014 - ncbi.nlm.nih.gov
Background: The heartwood extract of A. catechu, called pale catechu or “Katha” in Hindi
has been widely used in traditional Indian medicinal system. Although various …

[HTML][HTML] Glycyrrhizin induces reactive oxygen species-dependent apoptosis and cell cycle arrest at G0/G1 in HPV18+ human cervical cancer HeLa cell line

A Farooqui, F Khan, I Khan, IA Ansari - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Cervical cancer is the fourth most common cancer among women worldwide and is a major
cause of morbidity and mortality. High-risk Human Papilloma Virus (mostly type 16 & 18) …

Induction of apoptosis by epigallocatechin-3-gallate in human lymphoblastoid B cells

C Noda, J He, T Takano, C Tanaka, T Kondo… - Biochemical and …, 2007 - Elsevier
(−)-Epigallocatechin-3-gallate (EGCG), a major constituent of green tea polyphenols, has
been shown to suppress cancer cell proliferation and induce apoptosis. In this study we …

Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is …

SV Singh, Y Zeng, D Xiao, VG Vogel, JB Nelson… - Molecular cancer …, 2005 - AACR
The present study was undertaken to gain insights into the molecular mechanism of cell
death (apoptosis) by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora …

Anticancer effects of Annona glabra plant extracts in human leukemia cell lines

CB Cochrane, PKR Nair, SJ Melnick… - Anticancer …, 2008 - ar.iiarjournals.org
Annona glabra (pond apple), a tropical tree growing wild in the Americas and Asia, is used
in traditional medicine against several human ailments, including cancer. To validate the …

[HTML][HTML] Anticancer potential of Conium maculatum extract against cancer cells in vitro: Drug-DNA interaction and its ability to induce apoptosis through ROS …

J Mondal, AK Panigrahi… - Pharmacognosy …, 2014 - ncbi.nlm.nih.gov
Objective: Conium maculatum extract is used as a traditional medicine for cervix carcinoma
including homeopathy. However, no systematic work has so far been carried out to test its …

Glycyrrhizin mediates downregulation of notch pathway resulting in initiation of apoptosis and disruption in the cell cycle progression in cervical cancer cells

A Ahmad, RK Tiwari, M Saeed, I Ahmad… - Nutrition and …, 2022 - Taylor & Francis
Growing emphasis on exploring the antiproliferative potential of natural compounds has
gathered momentum for the formulation of anticancer drugs. In the present study, the …