Self-organizing spots get under your skin

D Dalle Nogare, AB Chitnis - PLoS Biology, 2017 - journals.plos.org
Sixty-five years after Turing first revealed the potential of systems with local activation and
long-range inhibition to generate pattern, we have only recently begun to identify the …

Module‐based complexity formation: periodic patterning in feathers and hairs

CM Chuong, CY Yeh, J Ting‐Xin… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
Patterns describe order which emerges from homogeneity. Complex patterns on the
integument are striking because of their visibility throughout an organism's lifespan. Periodic …

Cyclical dermal micro-niche switching governs the morphological infradian rhythm of mouse zigzag hair

M Takeo, K Toyoshima, R Fujimoto, T Iga… - Nature …, 2023 - nature.com
Biological rhythms are involved in almost all types of biological processes, not only
physiological processes but also morphogenesis. Currently, how periodic morphological …

Distinct mechanisms underlie pattern formation in the skin and skin appendages

RB Widelitz, RE Baker, M Plikus, CM Lin… - … Research Part C …, 2006 - Wiley Online Library
Patterns form with the break of homogeneity and lead to the emergence of new structure or
arrangement. There are different physiological and pathological mechanisms that lead to the …

Hierarchical patterning modes orchestrate hair follicle morphogenesis

JD Glover, KL Wells, F Matthäus, KJ Painter, W Ho… - PLoS …, 2017 - journals.plos.org
Two theories address the origin of repeating patterns, such as hair follicles, limb digits, and
intestinal villi, during development. The Turing reaction–diffusion system posits that …

Towards an integrated experimental–theoretical approach for assessing the mechanistic basis of hair and feather morphogenesis

KJ Painter, GS Hunt, KL Wells… - Interface …, 2012 - royalsocietypublishing.org
In his seminal 1952 paper,'The Chemical Basis of Morphogenesis', Alan Turing lays down a
milestone in the application of theoretical approaches to understand complex biological …

Periodic pattern formation during embryonic development

ZR Sudderick, JD Glover - Biochemical Society Transactions, 2024 - portlandpress.com
During embryonic development many organs and structures require the formation of series
of repeating elements known as periodic patterns. Ranging from the digits of the limb to the …

Turing patterning with and without a global wave

M Inaba, HIC Harn, CM Chuong - PLoS biology, 2019 - journals.plos.org
Periodic patterning represents a fundamental process in tissue morphogenesis. In chicken
dorsal skin, feather formation starts from the midline; then the morphogenetic wave …

[HTML][HTML] Gap junctions in Turing-type periodic feather pattern formation

CC Tseng, TE Woolley, TX Jiang, P Wu, PK Maini… - PLoS …, 2024 - journals.plos.org
Periodic patterning requires coordinated cell–cell interactions at the tissue level. Turing
showed, using mathematical modeling, how spatial patterns could arise from the reactions of …

Studies of Turing pattern formation in zebrafish skin

S Kondo, M Watanabe… - … Transactions of the …, 2021 - royalsocietypublishing.org
Skin patterns are the first example of the existence of Turing patterns in living organisms.
Extensive research on zebrafish, a model organism with stripes on its skin, has revealed the …