[HTML][HTML] Selenium nanoparticles alleviate ischemia reperfusion injury-induced acute kidney injury by modulating GPx-1/NLRP3/Caspase-1 pathway

S Wang, Y Chen, S Han, Y Liu, J Gao, Y Huang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Acute kidney injury (AKI) is a common critical illness in the clinic and currently
lacks effective treatment options. Ischemia reperfusion injury (IRI) is a major pathogenic …

Using green biosynthesized lycopene-coated selenium nanoparticles to rescue renal damage in glycerol-induced acute kidney injury in rats

A Al-Brakati, KF Alsharif, KJ Alzahrani… - International journal …, 2021 - Taylor & Francis
Purpose Selenium nanoparticles (SeNPs) have recently gained much attention in
nanomedicine applications owing to their unique biological properties. Biosynthesis of …

Kidney‐Targeted Nanoparticles Loaded with the Natural Antioxidant Rosmarinic Acid for Acute Kidney Injury Treatment

J Li, Q Duan, X Wei, J Wu, Q Yang - Small, 2022 - Wiley Online Library
Acute kidney injury (AKI) is a common clinical disease with high morbidity and mortality, and
with a lack of effective drugs for treatment. Oxidative stress is very important in the …

Selenium‐Doped Carbon Quantum Dots Act as Broad‐Spectrum Antioxidants for Acute Kidney Injury Management

ZT Rosenkrans, T Sun, D Jiang, W Chen… - Advanced …, 2020 - Wiley Online Library
The manifestation of acute kidney injury (AKI) is associated with poor patient outcomes, with
treatment options limited to hydration or renal replacement therapies. The onset of AKI is …

Functionalized selenium nanoparticles with nephroprotective activity, the important roles of ROS-mediated signaling pathways

Y Li, X Li, W Zheng, C Fan, Y Zhang… - Journal of Materials …, 2013 - pubs.rsc.org
The most frequent adverse effect of cisplatin-based chemotherapy is nephrotoxicity.
Oxidative stress has been implicated as an important mechanism in the pathogenesis of …

Nephroprotective role of selenium nanoparticles against glycerol-induced acute kidney injury in rats

G AlBasher, S Alfarraj, S Alarifi, S Alkhtani… - Biological trace element …, 2020 - Springer
Acute kidney injury (AKI) is a clinical syndrome associated with the incidence of
rhabdomyolysis (RM). The current study was carried out to evaluate whether selenium …

Ceria nanoparticles prophylactic used for renal ischemia-reperfusion injury treatment by attenuating oxidative stress and inflammatory response

L Zhou, S Tang, F Li, Y Wu, S Li, L Cui, J Luo, L Yang… - Biomaterials, 2022 - Elsevier
Renal ischemia-reperfusion (IR) injury (RIRI) is the leading cause of acute kidney injury
(AKI), a common disease with high morbidity and mortality. However, due to the lack of …

A novel role of Nano selenium and sildenafil on streptozotocin-induced diabetic nephropathy in rats by modulation of inflammatory, oxidative, and apoptotic pathways

MF El-Azab, AA Al-Karmalawy, SA Antar, PA Hanna… - Life sciences, 2022 - Elsevier
Aims The present study aimed to investigate the effect of nano selenium, sildenafil, and their
combination on inflammation, oxidative stress, and apoptosis in streptozotocin-induced …

Biogenic nanoselenium particles effectively attenuate oxidative stress-induced intestinal epithelial barrier injury by activating the Nrf2 antioxidant pathway

D Song, Y Cheng, X Li, F Wang, Z Lu… - … Applied Materials & …, 2017 - ACS Publications
In the present study, a new form of selenium nanoparticle (biogenic nanoselenium (BNS)
particles) was synthesized using bacteria. The protection of BNS particles against oxidative …

[HTML][HTML] Selenium nanoparticles for targeted stroke therapy through modulation of inflammatory and metabolic signaling

H Amani, R Habibey, F Shokri, SJ Hajmiresmail… - Scientific reports, 2019 - nature.com
Ischemic cerebral stroke is a major cause of death and morbidity. Currently, no
neuroprotective agents have been shown to impact the clinical outcomes in cerebral stroke …