Repeated pain during brain development can have long-term consequences in both
humans and animals. We previously showed that maternal care provided to pups …

Repeated pain during a critical period of development can have long-term behavioral and
physiological consequences in both human and animals. We previously showed that rat …

Early preterm neonates in the Neonatal Intensive Care Unit (NICU) are subjected to
repeated painful procedures which could sensitize their responses to pain and potentiate …

The intensive care necessary for premature newborns is characterized by multiple
procedures, many of which are painful. Given emerging evidence that such early pain during …

Human preterm neonates are subjected to repetitive pain during neonatal intensive care.
We hypothesized that exposure to repetitive neonatal pain may cause permanent or long …

Infants spending extended time in the neonatal intensive care unit are at greater risk of
developing a variety of mental health problems later in life, possibly due to exposure to …

Neonatal pain and stress induce long-term changes in pain sensitivity. Therefore their
interrelation is a topical subject of clinical and basic research. The present study …

Until recently, nociceptive experiences were rare for neonates. In evolutionary terms, this
may be the reason why pain-modulating systems are immature at birth (Winberg 1998) …

Preterm infants undergoing untreated, repeated painful procedures as part of their early
experience are more likely to behave differently to pain as they mature than infants who …

Background and aims Newborn infants are vulnerable to procedural stress and pain
exposure on the first weeks of life that represents a critical period for the development of …