Chemokines and Chemokine Receptors in Cancer: An Update

NM Elemam, AA Maghazachi - Handbook of Cancer and Immunology, 2023 - Springer
The chemokine family is composed of small chemotactic cytokines and receptors that
mediate the infiltration of various immune cells. According to the position of the cysteine …

[HTML][HTML] Chemokines and chemokine receptors: new targets for cancer immunotherapy

V Mollica Poeta, M Massara, A Capucetti… - Frontiers in …, 2019 - frontiersin.org
Immunotherapy is a clinically validated treatment for many cancers to boost the immune
system against tumor growth and dissemination. Several strategies are used to harness …

[HTML][HTML] Chemokines and their receptors: multifaceted roles in cancer progression and potential value as cancer prognostic markers

HTT Do, CH Lee, J Cho - Cancers, 2020 - mdpi.com
Chemokines are chemotactic cytokines that mediate immune cell chemotaxis and lymphoid
tissue development. Recent advances have indicated that chemokines and their cognate …

[PDF][PDF] Expanding role of chemokines and their receptors in cancer

M Arya, HRH Patel - Expert review of anticancer therapy, 2003 - Taylor & Francis
Cancer metastasis is no longer thought to be a random event and different types of cancer
have specific metastatic sites. Several explanations for these metastatic patterns have been …

[HTML][HTML] Consider the chemokines: a review of the interplay between chemokines and T cell subset function

M Strazza, A Mor - Discovery medicine, 2017 - ncbi.nlm.nih.gov
Subsets of T cells can be classified by the functions executed or by the anatomic location at
which they operate. In vitro analysis of T cell subsets and even commercial kits for subset …

Chemokines in cancer

MJ Frederick, GL Clayman - Expert reviews in molecular medicine, 2001 - cambridge.org
Chemokines are small, chemotactic cytokines that direct migration of leukocytes, activate
inflammatory responses and participate in many other pleiotropic functions, including …

[HTML][HTML] Advances in research on the effects and mechanisms of chemokines and their receptors in cancer

J Xu, J Li, Q Chen, EA Shestakova… - Frontiers in …, 2022 - frontiersin.org
Cancer is a common and intractable disease that seriously affects quality of life of patients
and imposes heavy economic burden on families and the entire society. Current …

Role of chemokine systems in cancer and inflammatory diseases

H Li, M Wu, X Zhao - MedComm, 2022 - Wiley Online Library
Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

Chemokines in cancer development and progression and their potential as targeting molecules for cancer treatment

N Mukaida, S Sasaki, T Baba - Mediators of inflammation, 2014 - Wiley Online Library
Chemokines were initially identified as bioactive substances, which control the trafficking of
inflammatory cells including granulocytes and monocytes/macrophages. Moreover …

Chemokine receptor signaling and the hallmarks of cancer

RA Lacalle, R Blanco, L Carmona-Rodríguez… - International review of …, 2017 - Elsevier
The chemokines are a family of chemotactic cytokines that mediate their activity by acting on
seven-transmembrane-spanning G protein-coupled receptors. Both the ability of the …