Are reactive oxygen species always detrimental to pathogens?

CN Paiva, MT Bozza - Antioxidants & redox signaling, 2014 - liebertpub.com
Reactive oxygen species (ROS) are deadly weapons used by phagocytes and other cell
types, such as lung epithelial cells, against pathogens. ROS can kill pathogens directly by …

Roles of reactive oxygen species in cell signaling pathways and immune responses to viral infections

Z Li, X Xu, X Leng, M He, J Wang, S Cheng, H Wu - Archives of virology, 2017 - Springer
Several biological processes as well as infectious agents, physiological or environmental
stress, and perturbed antioxidant response can promote oxidative stress. Oxidative stress …

[HTML][HTML] Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Beyond oxidative stress: an immunologist's guide to reactive oxygen species

C Nathan, A Cunningham-Bussel - Nature Reviews Immunology, 2013 - nature.com
Reactive oxygen species (ROS) react preferentially with certain atoms to modulate functions
ranging from cell homeostasis to cell death. Molecular actions include both inhibition and …

Reactive oxygen and nitrogen species during viral infections

CG Molteni, N Principi, S Esposito - Free radical research, 2014 - Taylor & Francis
Oxygen and nitrogen radicals are frequently produced during viral infections. These radicals
are not only a physiological mechanism for pathogen clearance but also result in many …

[HTML][HTML] Effect of reactive oxygen species on the endoplasmic reticulum and mitochondria during intracellular pathogen infection of mammalian cells

J Lee, CH Song - Antioxidants, 2021 - mdpi.com
Oxidative stress, particularly reactive oxygen species (ROS), are important for innate
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …

Oxidative stress during viral infection: a review

KB Schwarz - Free Radical Biology and Medicine, 1996 - Elsevier
The purpose of this review is to analyze the role of reactive oxygen species (ROS) in the
pathogenesis of viral infections, an area of research that has recently gained momentum …

How the redox state regulates immunity

L Mullen, M Mengozzi, EM Hanschmann… - Free Radical Biology …, 2020 - Elsevier
Oxidative stress is defined as an imbalance between the levels of reactive oxygen species
(ROS) and antioxidant defences. The view of oxidative stress as a cause of cell damage has …

[HTML][HTML] Oxidative stress in infection and consequent disease

AV Ivanov, B Bartosch… - Oxidative Medicine and …, 2017 - ncbi.nlm.nih.gov
Viral, bacterial, and parasitic infections comprise a vast group of etiological agents that
cause acute or chronic diseases. According to WHO, they represent one of the major causes …

[HTML][HTML] Reactive oxygen species: Do they play a role in adaptive immunity?

EY Bassoy, M Walch, D Martinvalet - Frontiers in Immunology, 2021 - frontiersin.org
The immune system protects the host from a plethora of microorganisms and toxins through
its unique ability to distinguish self from non-self. To perform this delicate but essential task …