[HTML][HTML] NLRP3 inflammasome: checkpoint connecting innate and adaptive immunity in autoimmune diseases
Y Zhang, W Yang, W Li, Y Zhao - Frontiers in immunology, 2021 - frontiersin.org
Autoimmune diseases are a broad spectrum of human diseases that are characterized by
the breakdown of immune tolerance and the production of autoantibodies. Recently …
the breakdown of immune tolerance and the production of autoantibodies. Recently …
[HTML][HTML] Role of the NLRP3 inflammasome in autoimmune diseases
Z Li, J Guo, L Bi - Biomedicine & pharmacotherapy, 2020 - Elsevier
NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …
[HTML][HTML] Regulation of NLRP3 inflammasome by phosphorylation
N Song, T Li - Frontiers in immunology, 2018 - frontiersin.org
The cytosolic pattern recognition receptor (PRR) NOD-like receptor family, pyrin domain
containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns …
containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns …
The role of NLRP3 inflammasome in the pathogenesis of rheumatic disease
R Kong, L Sun, H Li, D Wang - Autoimmunity, 2022 - Taylor & Francis
Inflammasome is a molecular platform that is formed in the cytosolic compartment to mediate
host immune responses to infection and cellular damage. Inflammasome can activate …
host immune responses to infection and cellular damage. Inflammasome can activate …
[HTML][HTML] The NLRP3 inflammasome: Contributions to inflammation-related diseases
Y Chen, X Ye, G Escames, W Lei, X Zhang, M Li… - Cellular & Molecular …, 2023 - Springer
The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines …
innate immune responses by activating caspase-1 and the inflammatory cytokines …
[HTML][HTML] Posttranslational regulation of the NLR family pyrin domain-containing 3 inflammasome
DW Shim, KH Lee - Frontiers in immunology, 2018 - frontiersin.org
The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a multi-
protein complex that can be activated by a variety of pathogen-associated molecular …
protein complex that can be activated by a variety of pathogen-associated molecular …
The NLRP3 inflammasome: Mechanism of action, role in disease and therapies
L Wang, AV Hauenstein - Molecular aspects of medicine, 2020 - Elsevier
NLRP3 is the best characterized cytosolic nod-like pattern recognition receptor which can
detect microbial motifs, endogenous danger and stress signals. Activation of NLRP3 leads to …
detect microbial motifs, endogenous danger and stress signals. Activation of NLRP3 leads to …
NLRP3 inflammasome activation and cell death
The NLRP3 inflammasome is a cytosolic multiprotein complex composed of the innate
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …
NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma
Abstract The NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome is
an immunological sensor that detects a wide range of microbial-and host-derived signals …
an immunological sensor that detects a wide range of microbial-and host-derived signals …
Sensing damage by the NLRP3 inflammasome
JC Leemans, SL Cassel… - Immunological reviews, 2011 - Wiley Online Library
The NLRP3 inflammasome is activated in response to a variety of signals that are indicative
of damage to the host including tissue damage, metabolic stress, and infection. Upon …
of damage to the host including tissue damage, metabolic stress, and infection. Upon …