The BRAF V600E mutation, resulting from the BRAFT1799A transversion, is the most
common genetic mutation in papillary thyroid carcinoma (PTC), with a mean frequency close …

Context: Use of BRAF mutation in papillary thyroid cancer (PTC) has the potential to improve
risk stratification of this cancer. Objective: The objective of the study was to investigate the …

Objectives The genes RET and RAS, and more recently BRAF, have been shown to be
frequently mutated in human papillary thyroid carcinomas (PTC). The aim of this study was …

BRAF (7q24) encodes a serine/threonine protein kinase, and its expression level varies in
different tissues. Although a high prevalence of BRAF mutation has been suggested as an …

Papillary thyroid carcinoma (PTC) is the most frequent malignant neoplasm of the thyroid
originating from the thyroid follicular cell (TFC). Although the formation of PTC is believed to …

Context: Approximately 40% of papillary thyroid carcinomas (PTCs) harbor the BRAF V600E
mutation, which is significantly associated with the advanced clinicopathological features of …

Somatic mutations of the BRAF gene (BRAF V599E and BRAF K600E) were found to be
closely associated with different histotypes of papillary thyroid carcinoma (PTC). The V599E …

Papillary thyroid carcinoma (PTC) is the most common malignancy of the thyroid gland. The
high incidence of RET/PTC and Trk rearrangements or point mutations in RAS and c-MET …

Finkelstein A, Levy GH, Hui P, Prasad A, Virk R, Chhieng DC, Carling T, Roman SA, Sosa
JA, Udelsman R, Theoharis CG & Prasad ML (2012) Histopathology 60, 1052–1059 …

BRAF alterations represent a novel indicator of the progression and aggressiveness of
thyroid carcinogenesis. So, the main aim of the study was to elucidate the involvement of …