[HTML][HTML] Frailty and maximal exercise capacity in adult lung transplant candidates

AM Layton, HF Armstrong, MR Baldwin… - Respiratory …, 2017 - Elsevier
Background Frail lung transplant candidates are more likely to be delisted or die without
receiving a transplant. Further knowledge of what frailty represents in this population will …

Frailty phenotypes, disability, and outcomes in adult candidates for lung transplantation

JP Singer, JM Diamond, CJ Gries… - American journal of …, 2015 - atsjournals.org
Rationale: Frailty is associated with morbidity and mortality in abdominal organ
transplantation but has not been examined in lung transplantation. Objectives: To examine …

Frailty trajectories in adult lung transplantation: a cohort study

A Venado, C McCulloch, JR Greenland, P Katz… - The Journal of Heart and …, 2019 - Elsevier
BACKGROUND Frailty is common in adults with advanced lung disease and is associated
with death before and after lung transplantation. We aimed to determine whether frailty …

Development of the lung transplant frailty scale (LT-FS)

JP Singer, JD Christie, JM Diamond… - The Journal of Heart and …, 2023 - Elsevier
Background Existing measures of frailty developed in community dwelling older adults may
misclassify frailty in lung transplant candidates. We aimed to develop a novel frailty scale for …

[HTML][HTML] Frailty phenotypes and mortality after lung transplantation: a prospective cohort study

JP Singer, JM Diamond, MR Anderson, PP Katz… - American Journal of …, 2018 - Elsevier
Frailty is associated with increased mortality among lung transplant candidates. We sought
to determine the association between frailty, as measured by the Short Physical …

Frailty as a predictor of mortality in patients with interstitial lung disease referred for lung transplantation

E Montgomery, PS Macdonald, PJ Newton… - …, 2020 - journals.lww.com
Background. Frailty is a clinically recognized syndrome of decreased physiological reserve
and a key contributor to suboptimal clinical outcomes in various lung disease groups …

Frailty and clinical benefits with lung transplantation

D Rozenberg, S Mathur, L Wickerson… - The Journal of Heart and …, 2018 - Elsevier
BACKGROUND The Fried frailty phenotype is associated with morbidity and mortality in lung
transplant (LTx) candidates, but its clinical application and association with post-transplant …

[HTML][HTML] Subphenotypes of frailty in lung transplant candidates

JP Singer, CS Calfee, K Delucchi, JM Diamond… - American Journal of …, 2023 - Elsevier
Heterogeneous frailty pathobiology might explain the inconsistent associations observed
between frailty and lung transplant outcomes. A Subphenotype analysis could refine frailty …

Pretransplant frailty is associated with decreased survival after lung transplantation

ME Wilson, AP Vakil, P Kandel, C Undavalli… - The Journal of Heart and …, 2016 - Elsevier
Background Frailty is a condition of increased vulnerability to adverse health outcomes.
Although frailty is an important prognostic factor for many conditions, the effect of frailty on …

Frailty is common in lung transplant candidates and associated with poorer health-related quality of life

JP Singer, PP Katz, MY Dean, J Chen, B Su… - The Journal of Heart …, 2013 - jhltonline.org
Purpose Lung transplant (LT) aims to improve both survival and quality of life (HRQL). To
achieve this, a better understanding of the factors determining HRQL is needed. We tested …