Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging

G Shyamala, YC Chou, SG Louie, RC Guzman… - The Journal of steroid …, 2002 - Elsevier
At present, there is an extensive body of literature documenting the participation of estrogen
receptors (ER) and progesterone receptors (PR) in mammary gene expression. Yet, the …

The ontogeny and cellular distribution of estrogen receptors in normal mouse mammary gland

SZ Haslam, KA Nummy - The Journal of steroid biochemistry and …, 1992 - Elsevier
The appearance, epithelial and stromal cell distribution of estrogen receptors (ER) in normal
mouse mammary gland were determined between 1 and 10 weeks of age using …

Progesterone receptors-animal models and cell signaling in breast cancer: The role of oestrogen and progesterone receptors in human mammary development and …

E Anderson - Breast Cancer Research, 2002 - Springer
A relatively small number of cells in the normal human mammary gland express receptors
for oestrogen and progesterone (ER and PR), and there is almost complete dissociation …

Steroid receptors in human breast tumorigenesis and breast cancer progression

LC Murphy, P Watson - Biomedicine & pharmacotherapy, 2002 - Elsevier
Steroid hormones, in particular estrogen and progesterone, play important roles in normal
and neoplastic breast development. Alterations in both estrogen signaling and progesterone …

Mammary gland growth and development from the postnatal period to postmenopause: ovarian steroid receptor ontogeny and regulation in the mouse

JL Fendrick, AM Raafat, SZ Haslam - Journal of mammary gland biology …, 1998 - Springer
Ovarian steroid hormones play a critical role inregulating mammary gland growth and
development. Themammary gland sequentially acquires and cyclicallyexhibits proliferative …

Differential regulation of estrogen receptor (ER) α and ERβ in primate mammary gland

G Cheng, Y Li, Y Omoto, Y Wang, T Berg… - The Journal of …, 2005 - academic.oup.com
Abstract Estrogen, mainly estradiol (E2), and progesterone (P) are essential for the growth
and differentiation of the breast, but their roles in breast cancer are highly debated. To …

Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle

BA LESSEY, AP KILLAM, DA METZGER… - The Journal of …, 1988 - academic.oup.com
Estrogen receptors (ER) and progesterone receptors (PgR) were studied
immunohistochemically using specific antireceptor monoclonal antibodies in uterine tissue …

Progesterone receptor repression by estrogens in rat uterine epithelial cells

K Parczyk, R Madjno, H Michna, Y Nishino… - The Journal of Steroid …, 1997 - Elsevier
Measurements performed using cell lines or animal tissues have shown that the
progesterone receptor (PR) can be induced by estrogens. By use of immunohistochemistry …

Steroid receptors and proliferation in the human breast

RB Clarke - Steroids, 2003 - Elsevier
Despite recent gains in our knowledge of the hormonal control of proliferation and
differentiation in the rodent mammary gland, the factors regulating these processes in the …

Estrogen and progesterone signalling in the normal breast and its implications for cancer development

HN Hilton, CL Clarke, JD Graham - Molecular and cellular endocrinology, 2018 - Elsevier
The ovarian hormones estrogen and progesterone are master regulators of the development
and function of a broad spectrum of human tissues, including the breast, reproductive and …