[HTML][HTML] Comparison of performance and clinical utility of different methods for detecting anti-PLA2R antibody

T Wang, M Wang, W Yu, H Li, Z Zhao, J Shang - Clinica Chimica Acta, 2023 - Elsevier
Objectives This study aimed to compare the performance of enzyme-linked immunosorbent
assay (ELISA) and magnetic particle chemiluminescence immunoassay (MP-CLIA) for …

Serum phospholipase A2 receptor antibodies and immunoglobulin G subtypes in adult idiopathic membranous nephropathy: clinical value assessment

G Cheng, J Liu, A Gilbert, Y Cao, C An, Z Lv, C Wang… - Clinica Chimica …, 2019 - Elsevier
Background Idiopathic membranous nephropathy (IMN) is widely considered as an organ-
specific autoimmune disorder. Implicated in its pathogenesis are the phospholipase A2 …

Phospholipase A2 receptor autoantibodies and clinical outcome in patients with primary membranous nephropathy

E Hoxha, I Thiele, G Zahner, U Panzer… - Journal of the …, 2014 - journals.lww.com
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults,
with an uncertain clinical outcome. The characterization of the phospholipase A 2 receptor …

[HTML][HTML] Enhanced expression of the M-type phospholipase A2 receptor in glomeruli correlates with serum receptor antibodies in primary membranous nephropathy

E Hoxha, U Kneißler, G Stege, G Zahner, I Thiele… - Kidney international, 2012 - Elsevier
The M-type phospholipase A2 receptor (PLA 2 R) is the major target antigen in idiopathic
membranous nephropathy with detectable autoantibodies in the serum of up to 70% of …

Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy?

O Ragy, V Rautemaa, A Smith, P Brenchley… - PLoS …, 2023 - journals.plos.org
Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology
practice has not changed dramatically, with most nephrologists still relying on a kidney …

Detection of PLA2R autoantibodies before the diagnosis of membranous nephropathy

PD Burbelo, M Joshi, A Chaturvedi… - Journal of the …, 2020 - journals.lww.com
Background Circulating serum autoantibodies against the M-type phospholipase A2
receptor (PLA2R-AB) are a key biomarker in the diagnosis and monitoring of primary …

Prognostic value of PLA2R autoimmunity detected by measurement of anti-PLA2R antibodies combined with detection of PLA2R antigen in membranous nephropathy …

F Pourcine, K Dahan, F Mihout, M Cachanado… - PloS one, 2017 - journals.plos.org
Introduction Clinical course of membranous nephropathy (MN) is difficult to predict.
Measurement of circulating anti-PLA2R autoantibodies (PLA2R-Ab) and detection in …

Anti-phospholipase A2 receptor antibody and spontaneous remission in membranous nephropathy

M Diaz, I Agraz, MJ Soler - Clinical kidney journal, 2019 - academic.oup.com
Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome
in native kidney biopsies from adults. In 2009, antibodies to the M-type receptor of …

Definition of a new cut-off for the anti-phospholipase A2 receptor (PLA2R) autoantibody immunoassay in patients affected by idiopathic membranous nephropathy

M Tampoia, F Migliucci, C Villani, L Abbracciavento… - Journal of …, 2018 - Springer
Autoantibodies against phospholipase A2 receptor (PLA2R) are a sensitive and specific
marker for idiopathic membranous nephropathy (IMN). The aim of our study was to redefine …

Phospholipase A2 receptor 1 epitope spreading at baseline predicts reduced likelihood of remission of membranous nephropathy

B Seitz-Polski, H Debiec, A Rousseau… - Journal of the …, 2018 - journals.lww.com
The phospholipase A2 receptor (PLA2R1) is the major autoantigen in primary membranous
nephropathy. Several PLA2R1 epitopes have been characterized, and a retrospective study …