[HTML][HTML] Anti-PLA2R antibodies measured by ELISA predict long-term outcome in a prevalent population of patients with idiopathic membranous nephropathy
D Kanigicherla, J Gummadova, EA McKenzie… - Kidney international, 2013 - Elsevier
Antibodies to the phospholipase A2 receptor 1 (PLA2R1) have been reported in 70% of
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …
Epitope spreading of autoantibody response to PLA2R associates with poor prognosis in membranous nephropathy
B Seitz-Polski, G Dolla, C Payré… - Journal of the …, 2016 - journals.lww.com
The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …
[HTML][HTML] M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
LH Beck Jr, RGB Bonegio, G Lambeau… - … England Journal of …, 2009 - Mass Medical Soc
Background Idiopathic membranous nephropathy, a common form of the nephrotic
syndrome, is an antibody-mediated autoimmune glomerular disease. Serologic diagnosis …
syndrome, is an antibody-mediated autoimmune glomerular disease. Serologic diagnosis …
[HTML][HTML] Anti-PLA2R1 antibodies as prognostic biomarker in membranous nephropathy
AE van De Logt, J Justino, CH Vink… - Kidney International …, 2021 - Elsevier
Introduction Personalized treatment for patients with membranous nephropathy requires
accurate prediction of the disease course at an early stage. In this study, we evaluated the …
accurate prediction of the disease course at an early stage. In this study, we evaluated the …
[HTML][HTML] Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies
CP Larsen, NC Messias, FG Silva, E Messias… - Modern Pathology, 2013 - Elsevier
Autoantibody formation directed against phospholipase A2 receptor (PLA2R) 1 is the
underlying etiology in most cases of primary membranous glomerulopathy. This new …
underlying etiology in most cases of primary membranous glomerulopathy. This new …
Pathogenicity of human anti-PLA2R1 antibodies in minipigs: a pilot study
L Reinhard, T Wiech, A Reitmeier… - Journal of the …, 2023 - journals.lww.com
Background Primary membranous nephropathy (MN) is an autoimmune kidney disease in
which immune complexes are deposited beneath the epithelium in the glomeruli. The …
which immune complexes are deposited beneath the epithelium in the glomeruli. The …
Reappraisal of PLA2R1 in membranous nephropathy: immunostaining method influence and association with IgG4-dominant phenotype
S Hara, S Goto, N Kamiura, A Yoshimoto, T Naito… - Virchows Archiv, 2015 - Springer
The M-type phospholipase A2 receptor (PLA2R1) was identified recently as a specific target
antigen in idiopathic membranous nephropathy. However, the influence of different sample …
antigen in idiopathic membranous nephropathy. However, the influence of different sample …
[HTML][HTML] Response to immunosuppressive therapy in PLA2R- associated and non-PLA2R- associated idiopathic membranous nephropathy: a retrospective …
J Wang, Q Xie, Z Sun, N Xu, Y Li, L Wang, S Liu, J Xue… - BMC nephrology, 2017 - Springer
Background According to renal M type phospholipase A 2 receptor (PLA 2 R)
immunohistochemistry, idiopathic membranous nephropathy (IMN) could be categorized …
immunohistochemistry, idiopathic membranous nephropathy (IMN) could be categorized …
[HTML][HTML] Autoantibodies specific for the phospholipase A2 receptor in recurrent and de novo membranous nephropathy
H Debiec, L Martin, C Jouanneau, G Dautin… - American Journal of …, 2011 - Elsevier
Recent findings in idiopathic membranous nephropathy (MN) suggest that in most patients,
the disease is because of anti-phospholipase A 2 receptor (PLA 2 R1) autoantibodies. Our …
the disease is because of anti-phospholipase A 2 receptor (PLA 2 R1) autoantibodies. Our …
[HTML][HTML] Differential diagnosis of membranous nephropathy with autoantibodies to phospholipase A2 receptor 1
W Schlumberger, N Hornig, S Lange, C Probst… - Autoimmunity …, 2014 - Elsevier
Membranous nephropathy (MN) accounts for most cases of the nephrotic syndrome in
adults. Recently, studies on the underlying pathomechanisms led to the identification of the …
adults. Recently, studies on the underlying pathomechanisms led to the identification of the …