[HTML][HTML] Quantitative structural organization of normal adult human articular cartilage

EB Hunziker, TM Quinn, HJ Häuselmann - Osteoarthritis and cartilage, 2002 - Elsevier
Objective Data pertaining to the quantitative structural features and organization of normal
articular cartilage are of great importance in understanding its biomechanical properties and …

[HTML][HTML] Micromechanical mapping of early osteoarthritic changes in the pericellular matrix of human articular cartilage

RE Wilusz, S Zauscher, F Guilak - Osteoarthritis and cartilage, 2013 - Elsevier
Objective Osteoarthritis (OA) is a degenerative joint disease characterized by the
progressive loss of articular cartilage. While macroscale degradation of the cartilage …

[HTML][HTML] Comparison of cartilage histopathology assessment systems on human knee joints at all stages of osteoarthritis development

C Pauli, R Whiteside, FL Heras, D Nesic, J Koziol… - Osteoarthritis and …, 2012 - Elsevier
OBJECTIVE: To compare the MANKIN and OARSI cartilage histopathology assessment
systems using human articular cartilage from a large number of donors across the adult age …

A comparative study of articular cartilage thickness in the stifle of animal species used in human pre-clinical studies compared to articular cartilage thickness in the …

DD Frisbie, MW Cross… - Veterinary and …, 2006 - thieme-connect.com
Histological measurements of the thickness of non-calcified and calcified cartilage, as well
as the subchondral bone plate in five locations on the femoral trochlea and medial femoral …

MicroCT evaluation of normal and osteoarthritic bone structure in human knee specimens

V Patel, AS Issever, A Burghardt, A Laib… - Journal of …, 2003 - Wiley Online Library
Although trabecular bone structure has been evaluated, variation with knee compartment
and depth from joint surface is not completely understood. Cadaver knees were evaluated …

Tibial and femoral cartilage changes in knee osteoarthritis

FM Cicuttini, AE Wluka, SL Stuckey - Annals of the Rheumatic …, 2001 - ard.bmj.com
BACKGROUND Despite the increasing interest in using knee cartilage volume as an
outcome measure in studies of osteoarthritis (OA), it is unclear what components of knee …

[HTML][HTML] The validity of in vivo ultrasonographic grading of osteoarthritic femoral condylar cartilage: a comparison with in vitro ultrasonographic and histologic gradings

CL Lee, MH Huang, CY Chai, CH Chen, JY Su… - Osteoarthritis and …, 2008 - Elsevier
OBJECTIVES: To establish an ultrasonographic (US) grading for semiquantitative evaluation
of the femoral condylar cartilage of knee osteoarthritis (OA), in vivo, and compare the in vivo …

The cartilage thickness distribution in the tibiofemoral joint and its correlation with cartilage-to-cartilage contact

G Li, SE Park, LE DeFrate, ME Schutzer, L Ji, TJ Gill… - Clinical …, 2005 - Elsevier
Objective. The objective of this study was to investigate whether regions of cartilage in the
tibiofemoral joint where cartilage-to-cartilage contact occurred was thicker than other …

Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone

H Hulejova, V Barešová, Z Klézl, M Polanská, M Adam… - Cytokine, 2007 - Elsevier
Objective: The aim of this study was to investigate the expression of several cytokines, matrix
metalloproteinases (MMPs), and tissue inhibitor of matrix metalloproteinases (TIMP)-1 in …

[HTML][HTML] In situ compressive stiffness, biochemical composition, and structural integrity of articular cartilage of the human knee joint

T Franz, EM Hasler, R Hagg, C Weiler, RP Jakob… - Osteoarthritis and …, 2001 - Elsevier
Objective Reduction of compressive stiffness of articular cartilage has been reported as one
of the first signs of cartilage degeneration. For the measurement of in situ compressive …