Due to the increasing number of studies performed in the field of regenerative medicine
during the last two decades, more analytic studies are still needed to clarify the future …

Developing effective stem cell-based therapies requires the design of complex in vitro
culture systems for accurate representation of the physiological stem cell niche. Human …

Background Amniotic membrane is a highly promising cell source for tissue engineering.
Being part of the placenta, this tissue is abundantly available. It can be processed easily to …

The human amniotic membrane (HAM) contains two cell types from different embryological
origins. Human amnion epithelial cells (hAECs) are derived from the embryonic ectoderm …

Recent evidence has shown that amniotic fluid may be a novel source of fetal stem cells for
therapeutic transplantation. We previously developed a two-stage culture protocol to isolate …

Background aims. Emerging evidence suggests human placental membrane is a valuable
source of mesenchymal stromal cells (MSC). Amnion and chorion are tissues of early …

The clinical application of the fetal membranes dates back to nearly a century. Their use has
ranged from superficial skin dressings to surgical wound closure. The applications of the …

An urgent current need in regenerative medicine is that of identifying a plentiful, safe and
ethically acceptable stem cell source for the development of therapeutic strategies to restore …