Telomerase reverse transcriptase is part of the telomerase complex responsible for
maintaining telomere length and increasing the replicative capacity of progenitor cells …

Compounds, and methods of using the same, are provided which increase the expression of
telomerase reverse transcriptase (TERT) in a cell. These compounds and methods find use …

This invention provides purified telomerase and methods of purifying it. The methods involve
the use of several sequen tial steps, including the use of matrices that bind molecules …

Telomerase repressor proteins and nucleic acid compositions encoding the same are
provided. The Subject repressor pro teins bind to a repressor site in the TERT minimal …

Methods and compositions are provided for modulating, and generally upregulating, the
expression of telomerase reverse transcriptase (TERT) by blocking repression of TERT …

Method and compositions are provided for the determination of telomere length and
telomerase activity, as well as the ability to increase or decrease telomerase activity in the …

Method and compositions are provided for the determination of telomere length and
telomerase activity, as well as the ability to increase or decrease telomerase activity in the …

BACKGROUND 0003. The following discussion is intended to introduce the field of the
present invention to the reader. The citation of various references in this section should not …

The invention provides compositions comprising fragments of human telomerase reverse
transcriptase (hTERT) which can lead to telomere dysfunction in a cell and reduction of …

US9200327B2 - Diagnostic markers for treating cell proliferative disorders with telomerase
inhibitors - Google Patents US9200327B2 - Diagnostic markers for treating cell proliferative …