Telomerase comprises a reverse transcriptase and an internal RNA template that maintains
telomeres in many eukaryotes, and it is a well-validated cancer target. However, there is a …

BACKGROUND OF THE INVENTION The American population is aging. The fastest
groWing segment of the population is persons over 85 years of age, Who are expected to …

ThiaZolidinedione compounds, compositions, and methods of inhibiting telomerase activity
in vitro and treatment of telomerase mediated conditions or diseases eX vivo and in vivo are …

2005-03-11 Assigned to REGENTS OF THE UNIVERSITY OF COLORADO, THE
reassignment REGENTS OF THE UNIVERSITY OF COLORADO, THE ASSIGNMENT OF …

Pursuant to 35 USC S 119 (e), this application claims priority to the filing date of the US
Provisional Patent Application Ser. Nos.:(a) 60/300,115 filed Jun. 21, 2001; and (b) …

US6551774B1 - Diagnostic methods for conditions associated with elevated cellular levels
of telomerase activity - Google Patents US6551774B1 - Diagnostic methods for conditions …

The present invention relates generally to the field of diag nostic and prognostic assays such
as diagnostic assays for conditions associated with telomerase activity. More particu larly …

Jankovic et al.,“Telomere loss and cancer', Nature 350: 197 (1991). Gall,“Tying up loose
ends”, Nature 344: 108 (1990). Yu et al.,“In Vivo alteration of telomere Sequences and …

Methods and compositions are provided for modulating, and generally upregulating, the
expression of telomerase reverse transcriptase (TERT) by modulating Myc Repeat region …

1996-05-03 Assigned to GERON CORPORATION reassignment GERON CORPORATION
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …