Single-nucleotide polymorphism on exon 17 of insulin receptor gene influences insulin resistance in PCOS: a pilot study on north Indian women

S Gangopadhyay, N Agrawal, A Batra, BC Kabi… - Biochemical …, 2016 - Springer
Polycystic ovarian syndrome (PCOS), a major cause of infertility, is also strongly associated
with insulin resistance. Defects in insulin receptor signaling are considered as one of the …

[HTML][HTML] INSR gene variation is associated with decreased insulin sensitivity in Iraqi women with PCOs

MT Mutib, FB Hamdan, AR Al-Salihi - Iranian journal of …, 2014 - ncbi.nlm.nih.gov
Background: Polycystic ovarian syndrome (PCOS) is a complex, heterogeneous disorder of
uncertain etiology with strong genetic background. Insulin resistance is present in the …

Genetic variation in exon 17 of INSR is associated with insulin resistance and hyperandrogenemia among lean Indian women with polycystic ovary syndrome

S Mukherjee, N Shaikh, S Khavale… - European Journal of …, 2009 - academic.oup.com
Objective Polycystic ovary syndrome (PCOS) is a multigenic disorder, and insulin resistance
is one of its hallmark features. Polymorphisms in exon 17 of insulin receptor (INSR) gene are …

Molecular scanning of the insulin receptor gene in women with polycystic ovarian syndrome

JA Talbot, EJ Bicknell, M Rajkhowa… - The Journal of …, 1996 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a common disorder characterized by chronic
anovulation and infertility, hyperandrogenaemia, and frequently insulin resistance. This …

[PDF][PDF] An insight of association of insulin resistance with polycystic ovary syndrome

S Chakraborty, A Samaddar, N Das, SK Saha… - Indian J Clin Anat …, 2021 - academia.edu
Background: Polycystic ovary syndrome (PCOS), a multifaceted condition, often has salient
features like insulin resistance (IR). Abnormal alternation in insulin synthesis and function …

Genetic polymorphisms of INS, INSR and IRS-1 genes are not associated with polycystic ovary syndrome in Croatian women

L Skrgatic, D Pavicic Baldani, K Gersak… - Collegium …, 2013 - hrcak.srce.hr
Sažetak Obesity and insulin resistance is a common finding in patients with polycystic ovary
syndrome (PCOS). Significant number of PCOS women experience insulin resistance that is …

[HTML][HTML] Insulin receptor substrate 1 Gly972Arg (rs1801278) polymorphism is associated with obesity and insulin resistance in Kashmiri women with polycystic ovary …

SUA Rasool, M Nabi, S Ashraf, S Amin - Genes, 2022 - mdpi.com
Background: Polycystic ovary syndrome (PCOS) is commonly associated with metabolic
abnormalities such as hyperinsulinemia, insulin resistance and obesity. The genetic variants …

Insulin gene polymorphism in women with polycystic ovary syndrome

P Ferk, MP Perme, K Geršak - Journal of International …, 2008 - journals.sagepub.com
Insulin resistance is one of the main characteristics of polycystic ovary syndrome (PCOS)
and is probably genetically predisposed. Possible associations of variable nucleotide …

Molecular & genetic factors contributing to insulin resistance in polycystic ovary syndrome

S Mukherjee, A Maitra - Indian Journal of Medical Research, 2010 - journals.lww.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of unknown
etiology. Insulin resistance is very common and plays a central pathogenic role in PCOS …

[HTML][HTML] Rs1799817 in INSR associates with susceptibility to polycystic ovary syndrome

MH Daghestani - Journal of medical biochemistry, 2020 - ncbi.nlm.nih.gov
Background Insulin and its receptor (INSR) have been implicated in the etiology of the
polycystic ovarian syndrome (PCOS). Here, we investigate the association between INSR …