Background Polycystic ovary syndrome (PCOS) is a complex disease having both genetic
and environmental components. Candidate genes with insulin metabolism have been …

OBJECTIVE: To examine the prevalence and the effects of Gly972Arg (G972A) variant of
insulin receptor substrate-1 (IRS-1) in women with polycystic ovary syndrome (PCOS) …

Objective This study is designed to determine whether an association exists between single
nucleotide polymorphism (SNP) variant rs2252673 of insulin receptor (INSR) gene and …

Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorder.
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …

To assess the role of the insulin receptor gene in polycystic ovary syndrome (PCOS) we
performed a case-control study in a female population (n= 226) from Central Europe by …

To assess the role of insulin receptor, insulin receptor substrate (IRS)-1, and IRS-2 genes in
insulin resistance, we explored the genomic DNA in women with polycystic ovary syndrome …

Polycystic ovarian syndrome (PCOS) in reproductive-aged women is identified to be one of
the endocrine disorders. This heterogeneous disorder is categorized through oligo …

Polycystic ovary syndrome (PCOS) is a heterogeneous condition with unknown aetiology
which is considered to be the most common endocrine disorder in women of reproductive …

Type 2 diabetes and insulin resistance (IR) are characterized by severe anomalies in genes
expression rate including genes involved in insulin signal transduction. Post-transcriptional …

Background Blood insulin level is an important risk factor for numerous disorders. Individual
blood insulin level is known to be substantially influenced by genetic factors. Several genetic …