We wish to comment on reference intervals for the serum anion gap and osmolality. The
serum anion gap, which is most commonly defined as AG Na-Cl-TCO2, traditionally has had …

The osmolal gap (OG) 1 is calculated in the emergency department (ED) when ingestion of
ethylene glycol, methanol, isopropyl alcohol, acetone, or other osmotically active substances …

The Serum Anion Gap Page 1 Original Articles The Serum Anion Gap Has the Reference Interval
Really Fallen? William L. Roberts, MD, PhD, Robbyn D. Johnson, MTtASCP) 0 Objective—To …

The traditional anion gap [AG= Na–Cl–(total CO2)] mean value of 12 mEq/L was established
during the 1970s with analyzer methods that are no longer used widely. No studies have …

Background Plasma osmolality is a physic and chemical property of interest in emergency
medicine. This magnitude can be measured at the laboratory, but it is usually estimated with …

Background: There are several methods for calculating serum osmolality, and their
accordance with measured osmolality is the subject of controversy. Methods: The …

Osmolality is a measurement of the number of moles of dissolved particles per kg of solvent
(for clinical purposes, water is the solvent). Osmolarity is a measure of the number of …

Background Many studies have assessed the predictive accuracy of serum osmolality
equations. Different approaches for selecting a usable equation were compared using thirty …

Osmolal gap is the difference between the measured osmolality and a calculated osmolality
based on the major commonly measured osmotically active particles. The perceived gap …

Background Substituting whole blood osmolality for plasma osmolality could expedite
treatments otherwise delayed by the time required to separate erythrocytes from plasma …