The formation of low resistance pathways is one of the most common forms of cellular
interaction. Since its discovery between neurons (40) this form of cell-to-cell communication …

Gap junctions are plasma membrane specializations characterized as aggregates of
intramembranous particles in two apposed membranes meeting particle-to-particle in the 2 …

We have viewed the membrane specializations that occur at gap junctions from the inside
and outside of cells in replicas of quick-frozen and deep-etched samples. Gap junctions …

Current structural models of gap junctions indicate two apposed plasma membranes with
hexagonally packed hemichannels in each membrane aligning end to end. These channels …

X-ray crystallographic methods and electron microscope image analysis have been used to
correlate the structure and the chemical composition of gap junction plaques isolated intact …

Micrographs of mouse liver gap junctions, isolated with detergents, and negatively stained
with uranyl acetate, have been recorded by low-irradiation methods. Our Fourier-averaged …

Embryonic development requires extensive interaction between cells; cell-to-cell
communication through gap junctions may be one mechanism involved. Much correlative …

Publisher Summary This chapter discusses the functions of gap junction. The chapter
considers the methodological requirements for investigating gap junction functions, the …

Since the description of the gap junction (or nexus) in the late 1950s and 1960s as a site of
intercellular communication be-tween adjacent cells, a large amount of literature has …

Micrographs of isolated gap junction specimens, negatively stained with one molybdate,
three tungstate and three uranyl stains, were recorded at low and high irradiation. Fourier …