Norethindrone acetate 1.0 milligram and ethinyl estradiol 10 micrograms as an ultra low-dose oral contraceptive

DF Archer, ST Nakajima, AT Sawyer… - Obstetrics & …, 2013 - journals.lww.com
OBJECTIVE: To assess the efficacy, safety, and tolerability of an extended-duration,
combined hormonal oral contraceptive pill (OCP) that reduces the estrogen exposure by …

Efficacy, safety and sustainability of treatment continuation and results of an oral contraceptive containing 30 mcg ethinyl estradiol and 2 mg chlormadinone acetate, in …

HP Zahradnik, A Hanjalic-Beck - Contraception, 2008 - Elsevier
BACKGROUND: This open-label, noncontrolled study assessed the long-term efficacy and
tolerability of the monophasic combined low-dose oral contraceptive (OC) ethinyl estradiol …

Effectiveness and acceptability of progestogens in combined oral contraceptives–a systematic review

R Kulier, FM Helmerhorst, N Maitra, AM Gülmezoglu - Reproductive health, 2004 - Springer
Background The progestogen component of oral contraceptives (OCs) has undergone
changes since it was recognized that their chemical structure can influence the spectrum of …

Confirmation of the safety of combined oral contraceptives containing oestradiol on the risk of venous thromboembolism

G Grandi, F Facchinetti, J Bitzer - The European Journal of …, 2022 - Taylor & Francis
Hormonal contraceptives, in particular combined oral contraceptives (COCs), were designed
to avoid unintended pregnancy, with the fewest possible side effects and health risks. The …

Oral contraceptive generations–time to stop using a marketing myth to define nomenclature

MD Creinin, JT Jensen - Contraception, 2020 - contraceptionjournal.org
The use of the term ''generation” to describe different formulations of combined oral
contraceptives (COCs) has no basis in pharmacology and creates confusion when used to …

[HTML][HTML] Endocrine and metabolic effects of an oral contraceptive containing estetrol and drospirenone

C Klipping, I Duijkers, M Mawet, C Maillard, A Bastidas… - Contraception, 2021 - Elsevier
Objectives To evaluate the effect on endocrine and metabolic parameters of a new
combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP) …

Hemostatic effects of a novel estradiol-based oral contraceptive: an open-label, randomized, crossover study of estradiol valerate/dienogest versus ethinylestradiol …

C Klipping, I Duijkers, S Parke, U Mellinger, M Serrani… - Drugs in R & D, 2011 - Springer
Background: A novel estradiol-based combined oral contraceptive (COC) is currently
available in many countries worldwide, including Europe and the US. Based on previous …

Cycle control with oral contraceptives containing 20 μg of ethinyl estradiol: a multicenter, randomized comparison of levonorgestrel/ethinyl estradiol (100 μg/20 μg) …

A DelConte, F Loffer, GS Grubb - Contraception, 1999 - Elsevier
A randomized, open-label, multicenter study was undertaken to compare the effects of oral
contraceptives (OC) containing 100 μg levonorgestrel (LNG)/20 μg ethinyl estradiol …

Approaches to the replacement of ethinylestradiol by natural 17β-estradiol in combined oral contraceptives

H Hoffmann, C Moore, H Zimmermann, W Elger… - Experimental and …, 1998 - Elsevier
The strong hepatic estrogenic actions of ethinylestradiol (EE) are very likely to be the cause
of the cardiovascular morbidity related to the use of combined oral contraceptives (COCs) …

Efficacy, cycle control, and side effects of low-and lower-dose oral contraceptives: a randomized trial of 20 μg and 35 μg estrogen preparations

MJ Rosenberg, A Meyers, V Roy - Contraception, 1999 - Elsevier
Estrogen content represents a tradeoff between cycle control and side effects, but few direct
comparisons of 20 and 30/35 μg preparations are available. To address this issue, we …