Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality worldwide. A
transition from an anti-inflammatory state to a pro-inflammatory state in the mother and at the …

Preterm birth (PTB)(delivery before 37 weeks' gestation) is a leading cause of neonatal
death and disease in industrialized and developing countries alike. Infection (most notably …

In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Pregnancy is a state of immunological balance during which the mother and the developing
fetus must tolerate each other while maintaining sufficient immunocompetence to ward off …

Regulatory T cells (Tregs) have been exhaustively investigated during early pregnancy;
however, their role later in gestation is poorly understood. Herein, we report that functional …

Preterm labor commonly precedes preterm birth, the leading cause of perinatal morbidity
and mortality worldwide. Most research has focused on establishing a causal link between …

Preterm birth is the leading cause of neonatal morbidity and mortality. Although the
underlying causes of pregnancy-associated complication are numerous, it is well …

Infection-driven inflammation in pregnancy is a major cause of spontaneous preterm birth
(PTB). Both systemic infection and bacterial ascension through the vagina/cervix to the …

Objective To comprehensively characterize monocyte and neutrophil responses to E. coli
and its product [lipopolysaccharide (LPS) or endotoxin] in vitro during pregnancy. Material or …

Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …