The impact of next-generation sequencing technology on genetics
ER Mardis - Trends in genetics, 2008 - cell.com
If one accepts that the fundamental pursuit of genetics is to determine the genotypes that
explain phenotypes, the meteoric increase of DNA sequence information applied toward that …
explain phenotypes, the meteoric increase of DNA sequence information applied toward that …
Coming of age: ten years of next-generation sequencing technologies
Since the completion of the human genome project in 2003, extraordinary progress has
been made in genome sequencing technologies, which has led to a decreased cost per …
been made in genome sequencing technologies, which has led to a decreased cost per …
Next-generation DNA sequencing methods
ER Mardis - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Recent scientific discoveries that resulted from the application of next-generation DNA
sequencing technologies highlight the striking impact of these massively parallel platforms …
sequencing technologies highlight the striking impact of these massively parallel platforms …
Beyond assembly: the increasing flexibility of single-molecule sequencing technology
The maturation of high-throughput short-read sequencing technology over the past two
decades has shaped the way genomes are studied. Recently, single-molecule, long-read …
decades has shaped the way genomes are studied. Recently, single-molecule, long-read …
Next-generation sequencing strategies
SE Levy, BE Boone - Cold Spring Harbor …, 2019 - perspectivesinmedicine.cshlp.org
More than a decade ago, the term “next-generation” sequencing was coined to describe
what was, at the time, revolutionary new methods to sequence RNA and DNA at a faster …
what was, at the time, revolutionary new methods to sequence RNA and DNA at a faster …
Next-generation sequencing data interpretation: enhancing reproducibility and accessibility
A Nekrutenko, J Taylor - Nature Reviews Genetics, 2012 - nature.com
Areas of life sciences research that were previously distant from each other in ideology,
analysis practices and toolkits, such as microbial ecology and personalized medicine, have …
analysis practices and toolkits, such as microbial ecology and personalized medicine, have …
An integrated framework for discovery and genotyping of genomic variants from high-throughput sequencing experiments
Recent advances in high-throughput sequencing (HTS) technologies and computing
capacity have produced unprecedented amounts of genomic data that have unraveled the …
capacity have produced unprecedented amounts of genomic data that have unraveled the …
A vision for the future of genomics research
FS Collins, ED Green, AE Guttmacher, MS Guyer… - nature, 2003 - nature.com
A vision for the future of genomics research | Nature Skip to main content Thank you for visiting
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SNP discovery and genotyping for evolutionary genetics using RAD sequencing
PD Etter, S Bassham, PA Hohenlohe… - Molecular methods for …, 2011 - Springer
Next-generation sequencing technologies are revolutionizing the field of evolutionary
biology, opening the possibility for genetic analysis at scales not previously possible …
biology, opening the possibility for genetic analysis at scales not previously possible …
Advances in sequencing technology
EY Chan - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
Faster sequencing methods will undoubtedly lead to faster single nucleotide polymorphism
(SNP) discovery. The Sanger method has served as the cornerstone for genome sequence …
(SNP) discovery. The Sanger method has served as the cornerstone for genome sequence …