Rituximab in relapsing and progressive forms of multiple sclerosis: a systematic review

T Castillo-Trivino, D Braithwaite, P Bacchetti… - PloS one, 2013 - journals.plos.org
Background Rituximab is an anti-CD20 monoclonal antibody approved for non Hodgkin
lymphoma and rheumatoid arthritis. It is being considered for the treatment of MS. Objectives …

Safety and efficacy of rituximab in multiple sclerosis: a retrospective observational study

BI Yamout, NK El-Ayoubi, J Nicolas… - Journal of …, 2018 - Wiley Online Library
Objective. To evaluate the efficacy and safety of rituximab in multiple sclerosis in a clinical
practice setting. Methods. Clinical data for all adult patients with multiple sclerosis (MS) …

Treatment of multiple sclerosis with rituximab: a multicentric Italian–Swiss experience

C Zecca, F Bovis, G Novi… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: Rituximab, an anti-CD20 monoclonal antibody leading to B lymphocyte
depletion, is increasingly used as an off-label treatment option for multiple sclerosis (MS) …

Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: a 52-week phase II trial

RT Naismith, L Piccio, JA Lyons, J Lauber, NT Tutlam… - Neurology, 2010 - AAN Enterprises
Objective: B cells and the humoral immune system have been implicated in the
pathogenesis of multiple sclerosis (MS). This study sought to evaluate the efficacy, safety …

Safety and efficacy of rituximab as first-and second line treatment in multiple sclerosis–A cohort study

HM Torgauten, KM Myhr, S Wergeland… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background Rituximab is increasingly used as off-label therapy in multiple sclerosis (MS).
More data are needed on safety and efficacy of rituximab, particularly in cohorts of de novo …

Efficacy and safety of rituximab in relapsing and progressive multiple sclerosis: a hospital-based study

C Alcalá, F Gascón, F Pérez-Miralles, S Gil-Perotín… - Journal of …, 2018 - Springer
Introduction Rituximab is considered as a potential therapeutic option in relapsing-remitting
(RRMS) and progressive forms (PMS) of multiple sclerosis (MS). Objective To investigate the …

Efficacy of rituximab in refractory RRMS

P Durozard, A Maarouf, C Boutiere… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Objective: To investigate the efficacy of rituximab as rescue therapy in patients with
relapsing-remitting multiple sclerosis (RRMS) and persistent disease activity confirmed by …

Efficacy and safety of rituximab in multiple sclerosis: Experience from a developing country

T Mathew, SK John, V Kamath, U Murgod… - Multiple Sclerosis and …, 2020 - Elsevier
Background Rituximab is increasingly being used in treatment of multiple Sclerosis (MS) in
our centers due to its easy availability, efficacy and favorable side effect profile. Here we …

Rituximab in multiple sclerosis at general hospital level

J Hellgren, A Risedal, K Källén - Acta Neurologica …, 2020 - Wiley Online Library
Objectives The use of rituximab (RTX) in multiple sclerosis (MS) is a rapidly increasing
choice of disease‐modifying therapy. Efficacy outside specialized university hospital‐based …

Rituximab combination therapy in relapsing multiple sclerosis

AH Cross, RS Klein, L Piccio - Therapeutic advances in …, 2012 - journals.sagepub.com
In multiple sclerosis (MS), the presence of B cells, plasma cells and excess
immunoglobulins in central nervous system lesions and in the cerebrospinal fluid implicate …