Epidemiologic studies have linked dioxin exposure to increased mortality caused by
ischemic heart disease. To test the hypothesis that dioxin exposure may constitute an …

Objective In this systematic review we evaluated the evidence on the association between
dioxin exposure and cardiovascular disease (CVD) mortality in humans. Data sources and …

The effects of chronic exposure to dioxin (2, 3, 7, 8,-tetrachlorodibenzo-p-dioxin [TCDD]) and
a dioxin-like compound (3, 3′, 4, 4′, 5-pentachlorobiphenyl [PCB126]) on the …

The developing cardiovascular system is a sensitive target of many environmental
pollutants, including dioxins, dioxin-like polychlorinated biphenyls (PCBs), and some …

Abstract The mechanisms by which 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) increases
the incidence of human cardiovascular disease are not known. We investigated the degree …

Epidemiological studies have suggested an association between exposure to dioxins and
cardiovascular morbidity and mortality. However, cardiotoxic effects of low doses of 2, 3, 7, 8 …

The last decade has seen a remarkable growth in the evidence establishing exposure to
environmental agents as a risk factor for cardiovascular disease (CVD). Most of this has …

Follow-up of the population exposed to dioxin after the 1976 accident in Seveso, Italy, was
extended to 1996. During the entire observation period, all-cause and all-cancer mortality …

OBJECTIVE: To investigate, in a population heavily exposed to 2, 3, 7, 8-tetrachlorodibenzo-
p-dioxin (TCDD), the possible unusual occurrence of diseases other than cancer …

Studies in our laboratory have demonstrated that subchronic 2, 3, 7, 8,-tetrachlorodibenzo-p-
dioxin (TCDD) exposure of adult mice results in hypertension, cardiac hypertrophy, and …