Honokiol for the treatment of neonatal pain and prevention of consequent neurobehavioral disorders
This study examined the short-and long-term neuroprotective and analgesic activity of
honokiol (a naturally occurring lignan isolated from Magnolia) on developing brains in …
honokiol (a naturally occurring lignan isolated from Magnolia) on developing brains in …
Effects of plant-derived analgesic compounds sinomenine and salvinorin A in infant rats
CJ Mascarenhas, R Liu, GA Barr - Journal of Integrative Medicine, 2020 - Elsevier
Objective Premature and ill neonates undergo painful but medically necessary procedures
while hospitalized. Although opiate drugs are administered as analgesics, problems …
while hospitalized. Although opiate drugs are administered as analgesics, problems …
[HTML][HTML] Neuro-modulating effects of honokiol: a review
Honokiol is a poly-phenolic compound that exerts neuroprotective properties through a
variety of mechanisms. It has therapeutic potential in anxiety, pain, cerebrovascular injury …
variety of mechanisms. It has therapeutic potential in anxiety, pain, cerebrovascular injury …
Effects of honokiol and magnolol on acute and inflammatory pain models in mice
YR Lin, HH Chen, CH Ko, MH Chan - Life Sciences, 2007 - Elsevier
The antinociceptive actions of honokiol and magnolol, two major bioactive constituents of
the bark of Magnolia officinalis, were evaluated using tail-flick, hot-plate and formalin tests in …
the bark of Magnolia officinalis, were evaluated using tail-flick, hot-plate and formalin tests in …
Neurite Outgrowth Effect of 4-O-methylhonokiol by Induction of Neurotrophic Factors Through ERK Activation
YK Lee, IS Choi, YH Kim, KH Kim, SY Nam… - Neurochemical …, 2009 - Springer
Compounds isolated from Magnolia officinalis such as magnolol, honokiol and obovatol
exhibit several pharmacological effects on CNS including depressant, anxiolytic and …
exhibit several pharmacological effects on CNS including depressant, anxiolytic and …
Comparative assessment of the anxiolytic-like activities of honokiol and derivatives
H Kuribara, E Kishi, M Kimura, ST Weintraub… - Pharmacology …, 2000 - Elsevier
Honokiol has previously been shown to be an effective anxiolytic-like agent in mice when
administered for 7 days at 0.2 mg/kg/day prior to evaluation in an elevated plus-maze, while …
administered for 7 days at 0.2 mg/kg/day prior to evaluation in an elevated plus-maze, while …
Inhibitory effects of honokiol on substantia gelatinosa neurons of the trigeminal subnucleus caudalis in juvenile mice
HTN Le, S Rijal, SH Jang, SA Park, SJ Park, W Jung… - Neuroscience, 2023 - Elsevier
Inhibitory neurotransmitters such as gamma-aminobutyric acid (GABA) and glycine are
known to be abundant in the substantia gelatinosa (SG) of the trigeminal subnucleus …
known to be abundant in the substantia gelatinosa (SG) of the trigeminal subnucleus …
[HTML][HTML] Neuropharmacological potential of honokiol and its derivatives from Chinese herb Magnolia species: understandings from therapeutic viewpoint
Honokiol is a neolignan biphenol found in aerial parts of the Magnolia plant species. The
Magnolia plant species traditionally belong to China and have been used for centuries to …
Magnolia plant species traditionally belong to China and have been used for centuries to …
Pharmacological rescue of nociceptive hypersensitivity and oxytocin analgesia impairment in a rat model of neonatal maternal separation
M Melchior, PE Juif, G Gazzo, N Petit-Demoulière… - Pain, 2018 - journals.lww.com
Oxytocin (OT), known for its neurohormonal effects around birth, has recently been
suggested for being a critical determinant in neurodevelopmental disorders. This …
suggested for being a critical determinant in neurodevelopmental disorders. This …
[HTML][HTML] Antihyperalgesic properties of honokiol in inflammatory pain models by targeting of NF-κB and Nrf2 signaling
The present study investigates the possible anti-nociceptive effect of intraperitoneal (ip)
honokiol: a phenolic compound originally isolated from Magnolia officinalis, in acute and …
honokiol: a phenolic compound originally isolated from Magnolia officinalis, in acute and …