RELMα is a small, secreted protein expressed by type 2 cytokine-activated “M2”
macrophages in helminth infection and allergy. At steady state and in response to type 2 …

Non-alcoholic steatohepatitis (NASH) is a common liver disease characterized by hepatic
lipid accumulation (steatosis) and inflammation. Currently, therapeutic options are poor and …

Appropriate inflammation is an effective weapon for the body to fight against harmful stimuli,
while excessive or prolonged inflammatory reactions could lead to tissue destruction …

The RON (recepteur d'origine nantais) receptor belongs to the MET proto-oncogene family
that is implicated in the oncogenesis of the gastrointestinal epithelium. The present study …

IFN-γ primes macrophages for antimicrobial activity, increased killing of intracellular
pathogens, and Ag processing and presentation to lymphocytes by cooperating with a …

Activated macrophages must carefully calibrate their inflammatory responses to balance
efficient pathogen control with inflammation-mediated tissue damage, but the molecular …

Reactive oxygen species (ROS) constitute a spectrum of oxygenic metabolites crucial in
modulating pathological organism functions. Disruptions in ROS equilibrium span various …

Ron, the tyrosine kinase receptor for macrophage-stimulating protein is responsible for
proliferation and migration of cells from different tissues. Ron can acquire oncogenic …

Recepteur d'origine nantais (RON, MST1R) is a single-span transmembrane receptor
tyrosine kinase (RTK) aberrantly expressed in numerous cancers, including various solid …

Epithelial to mesenchymal transition (EMT) is a process occurring during embryonic
development and cancer progression. Using recepteur d'origine nantais (RON)-expressing …