Oxidative stress is a major contributor to the pathogenesis of various inflammatory diseases.
Accumulating evidence has shown that oxidative stress is characterized by the …

Tumor associated macrophages (TAMs) play a major role in regulating mammary tumor
growth and in directing the responses of tumor infiltrating leukocytes in the …

The transcription factor NRF2 (nuclear factor [erythroid-derived 2]-like 2) plays crucial roles
in the defense mechanisms against oxidative stress and mediates anti-inflammatory actions …

Ren XL, Daa T, Yada N, Kashima K, Fujitomi Y, Yokoyama S. Expression and mutational
status of RON in neoplastic lesions of the breast: analysis of MSP/RON signaling in ductal …

Mito-SEPs are small open reading frame-encoded peptides that localize to the mitochondria
to regulate metabolism. Motivated by an intriguing negative association between mito-SEPs …

The epithelial-mesenchymal transition (EMT) is involved in neoplastic metastasis, and the
RON protein may be involved. In the present study, we determined the role and the …

Differentiation and recruitment of alternatively activated macrophages (AAMacs) are
hallmarks of several inflammatory conditions associated with infection, allergy, diabetes, and …

An appropriate inflammatory response plays critical roles in eliminating pathogens, whereas
an excessive inflammatory response can cause tissue damage. Runt-related transcription …

Signal transducer and activator of transcription 3 (STAT3) is implicated in inflammation
processing, but the mechanism of its regulation mostly remains limited to Janus kinase (JAK) …

Bacterial infection can trigger cellular stress programs, such as the unfolded protein
response (UPR), which occurs when misfolded proteins accumulate within the endoplasmic …