A SERIES of recent reports have demonstrated the covalent association of long polyadenylic
acid (poly A) sequences with mammalian cytoplasmic messenger RNA and with its putative …

POLYNUCLEOTIDE sequences rich in adenylic acid (poly (A)) have been found in a variety
of eukaryotic messenger, heterogenous nuclear (Hn) and viral RNAs1–5. Poly (A) tracts in …

Abstract POLYADENYLIC acid, poly (A), which was discovered some time ago in
mammalian cells1, 2, originates in the cell nucleus as part of HnRNA* and is also found in …

Polyadenylic acid (poly A) is covalently attached to the RNA molecules in which it occurs1–
4, but its exact location is not definitely established. It was at first thought to exist only at the …

Polyadenylic acid [poly (A)] segments containing 150 to 250 nucleotides appear to be
covalently linked to heterogeneous nuclear RNA (HnRNA) and messenger RNA (mRNA) in …

Poly (A) was first shown1 to be associated with cytoplasmic RNA in 1967. Since then it has
been shown to be associated with many RNAs that function as messenger or as intranuclear …

The poly (A) in HeLa cell messenger RNA appears to be associated with proteins in a poly
(A)-protein complex that can be isolated after treatment of mRNA-protein complexes with …

We have observed three effects of deletion mutations on polyadenylation of late SV40
mRNAs. The first class of mutants lack segments (-3 to-14 bp) between the 5'-AAUAAA-3' …

A NUMBER of laboratories have reported the isolation from eukaryotic cells of mRNAs
linked covalently at their 3′-OH termini to polyadenylic add (poly (A)) 1–4. The chain of …

The 70S genome of two RNA tumor viruses, murine sarcoma virus and avian myeloblastosis
virus, binds to Millipore filters in buffer with high salt concentration and to glass fiber filters …