Treatment of sulfur mustard (HD)‐induced lung injury
DR Anderson, SL Byers… - Journal of Applied …, 2000 - Wiley Online Library
An in vivo sulfur mustard (HD) vapor exposure model followed by bronchoalveolar lavage
was developed previously in this laboratory to study biochemical indicators of HD‐induced …
was developed previously in this laboratory to study biochemical indicators of HD‐induced …
Pathologic changes in rat lungs following acute sulfur mustard inhalation
DR Anderson, JJ Yourick, RB Moeller… - Inhalation …, 1996 - Taylor & Francis
Although the majority of deaths resulting from exposure to sulfur mustard (HD) have been
due to pulmonary dysfunction, there are no detailed accounts of the pathogenesis of HD …
due to pulmonary dysfunction, there are no detailed accounts of the pathogenesis of HD …
Inhalation exposure to sulfur mustard in the guinea pig model: clinical, biochemical and histopathological characterization of respiratory injuries
N Allon, A Amir, E Manisterski, I Rabinovitz… - Toxicology and applied …, 2009 - Elsevier
Guinea pigs (GP) were exposed (head only) in individual plethysmographs to various
concentrations of sulfur mustard vapor, determined online, using FTIR attached to flow …
concentrations of sulfur mustard vapor, determined online, using FTIR attached to flow …
Toxicity of sulphur mustard in adult rat lung organ culture
TW Sawyer, PE Wilde, P Rice, MT Weiss - Toxicology, 1995 - Elsevier
The toxicity of the chemical warfare agent sulphur mustard,(bis-(2-chloroethyl) sulphide,
HD), was examined in adult rat lung organ cultures. Assessment of HD-induced damage by …
HD), was examined in adult rat lung organ cultures. Assessment of HD-induced damage by …
Progressive lung injury, inflammation, and fibrosis in rats following inhalation of sulfur mustard
R Malaviya, EV Abramova, RC Rancourt… - Toxicological …, 2020 - academic.oup.com
Sulfur mustard (SM) inhalation causes debilitating pulmonary injury in humans which
progresses to fibrosis. Herein, we developed a rat model of SM toxicity which parallels …
progresses to fibrosis. Herein, we developed a rat model of SM toxicity which parallels …
Exposure–response effects of inhaled sulfur mustard in a large porcine model: a 6-h study
SJ Fairhall, BJA Jugg, RW Read, SJ Stubbs… - Inhalation …, 2010 - Taylor & Francis
Context: Inhalation of sulfur mustard (HD) vapor can cause life-threatening lung injury for
which there is no specific treatment. A reproducible, characterized in vivo model is required …
which there is no specific treatment. A reproducible, characterized in vivo model is required …
Inflammatory effects of inhaled sulfur mustard in rat lung
R Malaviya, VR Sunil, J Cervelli, DR Anderson… - Toxicology and applied …, 2010 - Elsevier
Inhalation of sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung
damage, is a significant threat to both military and civilian populations. The mechanisms …
damage, is a significant threat to both military and civilian populations. The mechanisms …
Mechanism underlying acute lung injury due to sulfur mustard exposure in rats
Z Xiaoji, M Xiao, X Rui, C Haibo… - Toxicology and …, 2016 - journals.sagepub.com
Sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung damage, is a
significant threat to both military and civilian populations. The mechanisms mediating the …
significant threat to both military and civilian populations. The mechanisms mediating the …
Inhalation exposure systems for the development of rodent models of sulfur mustard-induced pulmonary injury
WM Weber, DA Kracko, MR Lehman… - Toxicology …, 2010 - Taylor & Francis
Sulfur mustard (SM) is a chemical threat agent for which its effects have no current treatment.
Due to the ease of synthesis and dispersal of this material, the need to develop therapeutics …
Due to the ease of synthesis and dispersal of this material, the need to develop therapeutics …
Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity
Sulfur mustard (SM) is highly toxic to the lung inducing both acute and chronic effects
including upper and lower obstructive disease, airway inflammation, and acute respiratory …
including upper and lower obstructive disease, airway inflammation, and acute respiratory …
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