Experience in the treatment of dedifferentiated chondrosarcoma

AD Mitchell, K Ayoub, DC Mangham… - The Journal of Bone …, 2000 - boneandjoint.org.uk
Dedifferentiated chondrosarcoma is a rare, highly malignant variant of chondrosarcoma in
which a high-grade spindle-cell sarcoma coexists with a lower-grade chondroid tumour. We …

[HTML][HTML] Chondrosarcoma: biology, genetics, and epigenetics

WA Chow - F1000Research, 2018 - ncbi.nlm.nih.gov
Chondrosarcomas constitute a heterogeneous group of primary bone cancers characterized
by hyaline cartilaginous neoplastic tissue. They are the second most common primary bone …

Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment

JR Lex, S Evans, JD Stevenson, M Parry… - Clinical Sarcoma …, 2018 - Springer
Background Dedifferentiated chondrosarcomas (CS) are a high-grade variant of CS that
confers a 5-year survival of around 10–24%. Dedifferentiated CS arising from the pelvis …

Outcome of first‐line systemic treatment for unresectable conventional, dedifferentiated, mesenchymal, and clear cell chondrosarcoma

A van Maldegem, AP Conley, P Rutkowski… - The …, 2019 - academic.oup.com
Background Chondrosarcoma is a heterogeneous group of primary bone sarcoma with an
excellent overall survival after local therapy. However, the small percentage of patients who …

Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone

JG van Oosterwijk, D de Jong, MAJH van Ruler… - BMC cancer, 2012 - Springer
Background Chondrosarcoma is the second most common primary sarcoma of bone. High-
grade conventional chondrosarcoma and dedifferentiated chondrosarcoma have a poor …

The clinical approach towards chondrosarcoma

H Gelderblom, PCW Hogendoorn, SD Dijkstra… - The …, 2008 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: Classify
the chondrosarcoma subtypes. Engage in the diagnostic process of chondrosarcoma …

The molecular pathogenesis of dedifferentiated chondrosarcoma

A Sakamoto - Indian Journal of Orthopaedics, 2014 - Springer
Dedifferentiated chondrosarcomas are cartilaginous tumors that consist of two
distinguishable components, a lowgrade chondrosarcoma (chondrogenic) component and a …

Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment

JVMG Bovée, AM Cleton-Jansen… - The lancet …, 2005 - thelancet.com
Chondrosarcoma is a malignant cartilage-forming tumour of bone, of which distinct
clinicopathological subtypes are known. Conventional chondrosarcoma is notorious for its …

Grade 1 chondrosarcoma of bone: a diagnostic and treatment dilemma

RL Randall, W Gowski - Journal of the National Comprehensive Cancer …, 2005 - jnccn.org
Cartilaginous lesions of bone are relatively common and cover a large spectrum from latent
enchondroma to aggressive dedifferentiated chondrosarcoma. Differentiating among these …

Dedifferentiated chondrosarcoma: radiologic-pathologic correlation

G Bierry, A Feydy, F Larousserie, E Pluot… - Journal de …, 2010 - europepmc.org
Dedifferentiated chondrosarcomas are highly malignant tumors characterized by
conventional low-grade chondrosarcoma with abrupt transition to foci that have …