Molecular oncogenesis of chondrosarcoma: impact for targeted treatment

FM Speetjens, Y De Jong, H Gelderblom… - Current opinion in …, 2016 - journals.lww.com
As many different genetic alterations in chondrosarcoma have been identified, it is of the
utmost importance to classify druggable targets that may improve the prognosis of …

[HTML][HTML] Appendicular dedifferentiated chondrosarcoma: A management and survival study from the SEER database

MR Gonzalez, M Bryce-Alberti… - Journal of Bone …, 2022 - Elsevier
Introduction Dedifferentiated chondrosarcoma (DDC) is an aggressive osseous neoplasm
with a dismal prognosis. Treatment commonly involves limb-salvage surgery or amputation …

[HTML][HTML] Characteristics and Long-Term Outcome of Surgically Managed High-Grade Extremity Chondrosarcoma

TR Gulbrandsen, MK Skalitzky, MD Russell… - The Iowa orthopaedic …, 2023 - ncbi.nlm.nih.gov
Background Dedifferentiated chondrosarcoma (DCS) is a highly malignant variant that
portends a poor prognosis. Although factors such as clinico-pathological characteristics …

Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma

D Meijer, D de Jong, TC Pansuriya… - Genes …, 2012 - Wiley Online Library
Clear cell, mesenchymal, and dedifferentiated chondrosarcoma are rare, cartilaginous
tumors with limited treatment options other than surgery. Conventional chondrosarcomas …

Recent advances in the basic science of chondrosarcoma

RM Terek - Orthopedic Clinics, 2006 - orthopedic.theclinics.com
Chondrosarcoma are primary bone tumors that bear some relationship to the cartilage
phenotype. They can arise de novo (primary) or from a preexisting benign cartilage tumors …

Does ifosfamide therapy improve survival of patients with dedifferentiated chondrosarcoma?

S Kawaguchi, T Sun, PP Lin, M Deavers… - … and Related Research®, 2014 - Springer
Background Dedifferentiated chondrosarcoma remains a significant therapeutic challenge.
Studies performed to date have not identified efficacious chemotherapy regimens for this …

Potential Sampling Error in Fine Needle Aspiration Biopsy of Dedifferentiated Chondrosarcoma

AC Rinas, WG Ward, SE Kilpatrick - Acta cytologica, 2005 - karger.com
Background Dedifferentiated chondrosarcoma is a rare, poorly understood and often fatal
sarcoma that usually manifests as a high grade, non–cartilage-producing sarcoma …

Chondrosarcoma

RC Weinschenk, WL Wang… - JAAOS-Journal of the …, 2021 - journals.lww.com
Chondrosarcoma is the second most common primary bone tumor, with> 90% of cases
representing the primary conventional subtype. In addition to arising de novo, conventional …

Dedifferentiated chondrosarcoma: an aggressive variant of chondrosarcoma

G Bharath, R Burrah, K Shivakumar… - Asian …, 2015 - journals.sagepub.com
Dedifferentiated chondrosarcomas are a rare and aggressive subtype of chondrosarcoma
with a bimorphic pattern on histopathology. Rib is a rare site of dedifferentiated …

Chondrosarcoma: a clinical review

A Gazendam, S Popovic, N Parasu… - Journal of Clinical …, 2023 - mdpi.com
Chondrosarcomas are a diverse group of malignant cartilaginous matrix-producing
neoplasms. Conventional chondrosarcomas are a continuum of disease based on the …