Components of diesel exhaust particles diversely enhance a variety of respiratory diseases related to infection or allergy: extracted organic chemicals and the residual …

H Takano, R Yanagisawa, K Inoue - Journal of Clinical Biochemistry …, 2007 - jstage.jst.go.jp
Experimental and epidemiological studies have reported that diesel exhaust particles (DEP)
can aggravate a variety of respiratory diseases including infection or allergy. However, the …

Enhancement of acute lung injury related to bacterial endotoxin by components of diesel exhaust particles

R Yanagisawa, H Takano, K Inoue, T Ichinose… - Thorax, 2003 - thorax.bmj.com
Background: Diesel exhaust particles (DEP) synergistically aggravate acute lung injury
related to lipopolysaccharide (LPS) in mice, but the components in DEP responsible for this …

Components of diesel exhaust particles differentially affect Th1/Th2 response in a murine model of allergic airway inflammation

R Yanagisawa, H Takano, K Inoue… - Clinical & …, 2006 - Wiley Online Library
Background Diesel exhaust particles (DEP) can enhance various respiratory diseases.
However, it is unclear as to which components in DEP are associated with the …

Biological responses to diesel exhaust particles (DEPs) depend on the physicochemical properties of the DEPs

EJ Park, J Roh, MS Kang, SN Kim, Y Kim, S Choi - PloS one, 2011 - journals.plos.org
Diesel exhaust particles (DEPs) are the main components of ambient particulate materials,
including polyaromatic hydrocarbons (PAHs), n-PAHs, heavy metals, and gaseous …

Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial …

S Kawasaki, H Takizawa, K Takami… - American journal of …, 2001 - atsjournals.org
Epidemiologic and experimental studies suggest that diesel exhaust particles (DEPs) may
be related to increasing respiratory mortality and morbidity. We have shown that DEPs …

Effect of diesel exhaust particulate (DEP) on immune responses: contributions of particulate versus organic soluble components

PD Siegel, RK Saxena, QB Saxena… - Journal of Toxicology …, 2004 - Taylor & Francis
The effect of diesel exhaust particulate (DEP) exposure on innate, cellular and humoral
pulmonary immunity was studied using high-dose, acute-exposure rat, mouse, and cell …

Organic compounds from diesel exhaust particles elicit a proinflammatory response in human airway epithelial cells and induce cytochrome p450 1A1 expression

V Bonvallot, A Baeza-Squiban, A Baulig… - American journal of …, 2001 - atsjournals.org
Diesel exhaust particles (DEP) are known to enhance inflammatory responses in human
volunteers. In cultured human bronchial epithelial (16HBE) cells, they induce the release of …

Pulmonary exposure to diesel exhaust particles enhances coagulatory disturbance with endothelial damage and systemic inflammation related to lung inflammation

K Inoue, H Takano, M Sakurai, T Oda… - Experimental …, 2006 - journals.sagepub.com
Pulmonary exposure to diesel exhaust particles (DEP) enhances lung inflammation related
to bacterial endotoxin (lipopolysaccharide [LPS]) in mice. Severe lung inflammation can …

The dual effect of the particulate and organic components of diesel exhaust particles on the alteration of pulmonary immune/inflammatory responses and metabolic …

JYC Ma, JKH Ma - Journal of Environmental Science and Health …, 2002 - Taylor & Francis
Exposure to diesel exhaust particles (DEP) is an environmental and occupational health
concern. This review examines the cellular actions of the organic and the particulate …

Effects of organic chemicals derived from ambient particulate matter on lung inflammation related to lipopolysaccharide

K Inoue, H Takano, R Yanagisawa, S Hirano… - Archives of …, 2006 - Springer
The effects of components of ambient particulate matter (PM) on individuals with
predisposing respiratory disorders are not well defined. We have previously demonstrated …