Intranasal Oxytocin and Pain Reduction: Testing a Social Cognitive Mediation Model

P Long, JL Scholl, X Wang, NA Kallsen, EA Ehli… - Brain Sciences, 2023 - mdpi.com
Oxytocin is well known for its role in relationships and social cognition and has more
recently been implicated in pain relief and pain perception. Connections between prosocial …

Patients in pain: The effects of oxytocin on trust and decision making

PA Long, H Freeman - … on Human Factors and Ergonomics in …, 2019 - journals.sagepub.com
Oxytocin (OT) is a naturally occurring hormone produce by the hypothalamus. While a
growing body of work has focused on the role of OT in modulating human social cognition, a …

The relationship between oxytocin and empathy for others' pain: Testing the mediating effect of first-hand pain sensitivity

C Lin, S Zhuo, Q Zheng, X Li, W Peng - Physiology & Behavior, 2023 - Elsevier
Although previous studies have shown that oxytocin attenuates first-hand pain sensitivity,
studies of its effects on empathetic reactions to the observation of others' pain have yielded …

[HTML][HTML] Intranasal oxytocin and the stress-buffering effects of social support during experimentally induced pain: the role of attachment security

MME Riem, LE Kunst, WJ Kop - Journal of Affective Disorders, 2021 - Elsevier
Background This study examined whether intranasal oxytocin enhances the stress-buffering
effects of social support during experimentally induced pain, taking into account the role of …

Intranasal oxytocin effects on social cognition: a critique

SL Evans, O Dal Monte, P Noble, BB Averbeck - Brain research, 2014 - Elsevier
The last decade has seen a large number of published findings supporting the hypothesis
that intranasally delivered oxytocin (OT) can enhance the processing of social stimuli and …

Oxytocin and positive couple interaction affect the perception of wound pain in everyday life

AC Pfeifer, P Schroeder-Pfeifer, E Schneider… - Molecular …, 2020 - journals.sagepub.com
A large body of animal and human laboratory research has linked social interaction and
support to pain perception, with a possible role for the neuropeptide oxytocin as a …

In the nose or on the tongue? Contrasting motivational effects of oral and intranasal oxytocin on arousal and reward during social processing

J Kou, C Lan, Y Zhang, Q Wang, F Zhou, Z Zhao… - Translational …, 2021 - nature.com
Intranasal oxytocin exerts wide-ranging effects on socioemotional behavior and is proposed
as a potential therapeutic intervention in psychiatric disorders. However, following intranasal …

[HTML][HTML] Dissecting social decision-making: A spotlight on oxytocinergic transmission

G Coccia, F La Greca, M Di Luca… - Frontiers in Molecular …, 2022 - frontiersin.org
Social decision-making requires the ability to balance both the interests of the self and the
interests of others to survive in social environments. Empathy is essential to the regulation of …

Intranasal oxytocin administration is associated with enhanced endogenous pain inhibition and reduced negative mood states

BR Goodin, AJB Anderson, EL Freeman… - The Clinical journal …, 2015 - journals.lww.com
Objectives: This study examined whether the administration of intranasal oxytocin was
associated with pain sensitivity, endogenous pain inhibitory capacity, and negative mood …

Prosocial effects of oxytocin and clinical evidence for its therapeutic potential

N Striepens, KM Kendrick, W Maier… - Frontiers in …, 2011 - Elsevier
There has been unprecedented interest in the prosocial effects of the neuropeptide oxytocin
in humans over the last decade. A range of studies has demonstrated correlations between …