A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin
BackgroundThe neuropeptide oxytocin is proposed as a promising therapy for social
dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical …
dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical …
A preliminary examination of endogenous peripheral oxytocin in a pilot randomized clinical trial of oxytocin-enhanced psychotherapy for posttraumatic stress disorder
LM Sippel, CE King, AE Wahlquist… - Journal of clinical …, 2020 - journals.lww.com
Background Preclinical and clinical research suggests that the oxytocin system is implicated
in the development and maintenance of stress and anxiety-related psychiatric conditions …
in the development and maintenance of stress and anxiety-related psychiatric conditions …
Elevated salivary levels of oxytocin persist more than 7 h after intranasal administration
MH Van IJzendoorn, R Bhandari… - Frontiers in …, 2012 - frontiersin.org
We addressed the question how long salivary oxytocin levels remain elevated after
intranasal administration, and whether it makes a difference when 16 or 24 IU of oxytocin …
intranasal administration, and whether it makes a difference when 16 or 24 IU of oxytocin …
The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans
K MacDonald, TM MacDonald - Harvard review of psychiatry, 2010 - journals.lww.com
Oxytocin is a neuropeptide involved in a wide variety of social behaviors in diverse species.
Recent research on its effects in humans has generated an arresting picture of its role in the …
Recent research on its effects in humans has generated an arresting picture of its role in the …
Oxytocin increases the pleasantness of affective touch and orbitofrontal cortex activity independent of valence
Y Chen, B Becker, Y Zhang, H Cui, J Du… - European …, 2020 - Elsevier
Touch plays a crucial role in affiliative behavior and social communication. The
neuropeptide oxytocin is released in response to touch and may act to facilitate the …
neuropeptide oxytocin is released in response to touch and may act to facilitate the …
Sniffing oxytocin: Nose to brain or nose to blood?
S Yao, Y Chen, Q Zhuang, Y Zhang, C Lan, S Zhu… - Molecular …, 2023 - nature.com
In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …
Intranasal oxytocin does not reduce age-related difficulties in social cognition
Oxytocin is a neuropeptide that plays a key role in social processing and there are several
studies suggesting that intranasally administered oxytocin may enhance social cognitive …
studies suggesting that intranasally administered oxytocin may enhance social cognitive …
Oxytocin׳ s role in anxiety: A critical appraisal
K MacDonald, D Feifel - Brain research, 2014 - Elsevier
A growing literature suggests that the oxytocin (OT) system may play a role in human anxiety
states, anxiety-related traits, and moreover, that this system may be a target for the …
states, anxiety-related traits, and moreover, that this system may be a target for the …
Oxytocin and the social brain: neural mechanisms and perspectives in human research
M Kanat, M Heinrichs, G Domes - Brain research, 2014 - Elsevier
The present paper summarizes functional imaging studies investigating the effects of
intranasal oxytocin (OT) on brain responses to social stimuli. We aim to integrate previous …
intranasal oxytocin (OT) on brain responses to social stimuli. We aim to integrate previous …
[HTML][HTML] Intranasal oxytocin failed to affect chimpanzee (Pan troglodytes) social behavior
D Proctor, SE Calcutt, K Burke… - Animal behavior and …, 2016 - ncbi.nlm.nih.gov
Oxytocin has been suggested as a treatment to promote positive social interactions in
people with Autism Spectrum Disorders (ASD). However, it is difficult to test this effect …
people with Autism Spectrum Disorders (ASD). However, it is difficult to test this effect …