Cartilage progenitor/stem cells (CPCs) are promising seed cells for cartilage regeneration,
but their fate changes and regulatory mechanisms in osteoarthritis (OA) pathogenesis …

Osteoarthritis is a multifactorial disease characterized by cartilage degeneration, while
cartilage progenitor/stem cells (CPCs) are responsible for endogenous cartilage repair …

Objective To summarize the effect of cartilage progenitor cells (CPCs) and microRNA-140
(miR-140) on the repair of osteoarthritic cartilage injury, and analyze their clinical prospects …

Introduction Currently, osteoarthritis (OA) receives global increasing attention because it
associates severe joint pain and serious disability. Stem cells intra-articular injection therapy …

Bone marrow mesenchymal stem cell (BMSC) chondrogenic differentiation contributes to the
treatment of osteoarthritis (OA). Numerous studies have indicated that microRNAs (miRNAs) …

Objective MicroRNAs (miRNAs) play a key role in the differentiation of bone marrow–derived
mesenchymal stem cells (BMSCs) into chondrocytes. Our previous study found that novel …

Osteoarthritis, also known as degenerative arthritis or degenerative joint disease, causes
pain and disability worldwide. Cartilage regeneration is key to finding a cure for this disease …

Osteoarthritis (OA) is the most common joint disease; thus, understanding the pathological
mechanisms of OA initiation and progression is critical for OA treatment. MicroRNAs …

Cartilage matrix remodelling homeostasis is a crucial factor in maintaining cartilage integrity.
Loss of cartilage integrity is a typical characteristic of osteoarthritis (OA). Strategies aimed at …

Excessive subchondral angiogenesis is a key pathological feature of osteoarthritis (OA), as it
alters the balance of subchondral bone remodeling and causes progressive cartilage …